UGPE_BRUSU
ID UGPE_BRUSU Reviewed; 282 AA.
AC Q8FW08; G0KD34;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpE;
GN Name=ugpE; OrderedLocusNames=BRA0657, BS1330_II0651;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- FUNCTION: Part of the ABC transporter complex UgpABCE involved in sn-
CC glycerol-3-phosphate import. Probably responsible for the translocation
CC of the substrate across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC (UgpB). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000305}.
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DR EMBL; AE014292; AAN33846.1; -; Genomic_DNA.
DR EMBL; CP002998; AEM20122.1; -; Genomic_DNA.
DR RefSeq; WP_006192024.1; NZ_KN046805.1.
DR AlphaFoldDB; Q8FW08; -.
DR SMR; Q8FW08; -.
DR EnsemblBacteria; AEM20122; AEM20122; BS1330_II0651.
DR GeneID; 45053688; -.
DR KEGG; bms:BRA0657; -.
DR KEGG; bsi:BS1330_II0651; -.
DR PATRIC; fig|204722.21.peg.477; -.
DR HOGENOM; CLU_016047_1_1_5; -.
DR OMA; FNSMAAY; -.
DR Proteomes; UP000007104; Chromosome II.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0015794; P:glycerol-3-phosphate transmembrane transport; IEA:InterPro.
DR GO; GO:0001407; P:glycerophosphodiester transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR030165; UgpE.
DR PANTHER; PTHR43744:SF8; PTHR43744:SF8; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..282
FT /note="sn-glycerol-3-phosphate transport system permease
FT protein UgpE"
FT /id="PRO_0000290140"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 78..269
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 282 AA; 31992 MW; C7C8FD2C3F698660 CRC64;
MIEQRPVSNL IGHLILILGI IIVAFPIYYT FVASLMTSTQ IIRPPISLLP GDHLVENYRE
AIFGGVERVV GVSLERLLWN SFVVAMAIAV GKIIISFMSA FAIVFFRFPM RMFFFWMIFI
TLMLPVEVRI LPTYKVIVDL GMIDTYAGLT LPLMASATAT FLFRQFFLTI PGELVEAARI
DNAGPFRFMR DILLPLSKTN IAALFVILSI YGWTQYLWPL LVTNDAKMNT IIIGLRRMVD
WADASTSWNY VMVTAILAII PPILVVVLMQ RWFVKGLVET EK
