UGPE_SHIFL
ID UGPE_SHIFL Reviewed; 281 AA.
AC Q83PU7; Q7BYU1;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpE;
GN Name=ugpE; OrderedLocusNames=SF3469, S4294;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC sn-glycerol-3-phosphate; probably responsible for the translocation of
CC the substrate across the membrane. {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC (UgpB). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. UgpAE subfamily. {ECO:0000305}.
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DR EMBL; AE005674; AAN44928.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP19254.1; -; Genomic_DNA.
DR RefSeq; NP_709221.1; NC_004337.2.
DR RefSeq; WP_000572164.1; NZ_WPGW01000010.1.
DR AlphaFoldDB; Q83PU7; -.
DR SMR; Q83PU7; -.
DR STRING; 198214.SF3469; -.
DR EnsemblBacteria; AAN44928; AAN44928; SF3469.
DR EnsemblBacteria; AAP19254; AAP19254; S4294.
DR GeneID; 1026425; -.
DR GeneID; 67417078; -.
DR KEGG; sfl:SF3469; -.
DR KEGG; sfx:S4294; -.
DR PATRIC; fig|198214.7.peg.4089; -.
DR HOGENOM; CLU_016047_1_1_6; -.
DR OMA; IAFFIAW; -.
DR OrthoDB; 1074175at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0015794; P:glycerol-3-phosphate transmembrane transport; IEA:InterPro.
DR GO; GO:0001407; P:glycerophosphodiester transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR030165; UgpE.
DR PANTHER; PTHR43744:SF8; PTHR43744:SF8; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..281
FT /note="sn-glycerol-3-phosphate transport system permease
FT protein UgpE"
FT /id="PRO_0000292687"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 77..268
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 281 AA; 31472 MW; 8CAEE36109539810 CRC64;
MIENRPWLTI FSHTMLILGI AVILFPLYVA FVAATLDKQA VYAAPMTLIP GTHLLENIHN
IWVNGVGTNS APFWRMLLNS FVMAFSITLG KITVSMLSAF AIVWFRFPLR NLFFWMIFIT
LMLPVEVRIF PTVEVIANLK MLDSYAGLTL PLMASATATF LFRQFFMTLP DELVEAARID
GASPMRFFCD IVFPLSKTNL AALFVITFIY GWNQYLWPLL IITDVDLGTT VAGIKGMIAT
GEGTTEWNSV MAAMLLTLIP PVVIVLVMQR AFVRGLVDSE K
