UGPE_YERPE
ID UGPE_YERPE Reviewed; 281 AA.
AC Q7CKV5; Q74R29;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpE;
GN Name=ugpE; OrderedLocusNames=YPO3794, y0436, YP_3255;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC sn-glycerol-3-phosphate; probably responsible for the translocation of
CC the substrate across the membrane. {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC (UgpB). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. UgpAE subfamily. {ECO:0000305}.
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DR EMBL; AE009952; AAM84025.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS63423.1; -; Genomic_DNA.
DR EMBL; AL590842; CAL22380.1; -; Genomic_DNA.
DR PIR; AI0461; AI0461.
DR RefSeq; WP_002211522.1; NZ_WUCM01000048.1.
DR RefSeq; YP_002348671.1; NC_003143.1.
DR AlphaFoldDB; Q7CKV5; -.
DR SMR; Q7CKV5; -.
DR STRING; 214092.YPO3794; -.
DR PaxDb; Q7CKV5; -.
DR DNASU; 1145383; -.
DR EnsemblBacteria; AAM84025; AAM84025; y0436.
DR EnsemblBacteria; AAS63423; AAS63423; YP_3255.
DR GeneID; 66843355; -.
DR KEGG; ype:YPO3794; -.
DR KEGG; ypk:y0436; -.
DR KEGG; ypm:YP_3255; -.
DR PATRIC; fig|214092.21.peg.4315; -.
DR eggNOG; COG0395; Bacteria.
DR HOGENOM; CLU_016047_1_1_6; -.
DR OMA; IAFFIAW; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0015794; P:glycerol-3-phosphate transmembrane transport; IEA:InterPro.
DR GO; GO:0001407; P:glycerophosphodiester transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR030165; UgpE.
DR PANTHER; PTHR43744:SF8; PTHR43744:SF8; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..281
FT /note="sn-glycerol-3-phosphate transport system permease
FT protein UgpE"
FT /id="PRO_0000292690"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 77..268
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 281 AA; 31472 MW; 17610E0C81F81523 CRC64;
MIENRRGLDI FCHIMLIIGV LLILFPLYVA FVAASLDDSQ VFQAPMTLIP GPHLWQNISH
IWHAGVGNNS TPFGLMLLNS FVMAFAITVG KITVSILSAY AIVYFRFPLR NLFFWLIFLT
LMLPVEVRIF PTIEVIANLN LLDSYTGLTL PLMASATATF LFRQFFMTLP DELLEAARID
GAGAMRFFWD IVLPLSKTNL AALFVITFIY GWNQYLWPIL ITSDASMGTA VAGIRSMIST
SGAPTQWNQV MAAMILTLIP PVVVVLLMQR WFVRGLVDSE K
