ID   UGT47_CAEBR             Reviewed;         536 AA.
AC   A8WLF6;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   10-AUG-2010, sequence version 3.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Putative UDP-glucuronosyltransferase ugt-47;
DE            Short=UDPGT 47;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=ugt-47; ORFNames=CBG24767;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC         beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC         ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC         Evidence={ECO:0000250|UniProtKB:Q9BY64};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000255}.
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DR   EMBL; HE601485; CAP21301.3; -; Genomic_DNA.
DR   AlphaFoldDB; A8WLF6; -.
DR   SMR; A8WLF6; -.
DR   STRING; 6238.CBG24767; -.
DR   WormBase; CBG24767; CBP24717; WBGene00042804; Cbr-ugt-47.
DR   eggNOG; KOG1192; Eukaryota.
DR   HOGENOM; CLU_012949_1_3_1; -.
DR   InParanoid; A8WLF6; -.
DR   OMA; WKFESDE; -.
DR   OrthoDB; 508327at2759; -.
DR   Proteomes; UP000008549; Chromosome V.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   Pfam; PF00201; UDPGT; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome; Signal;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..536
FT                   /note="Putative UDP-glucuronosyltransferase ugt-47"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000396642"
FT   TRANSMEM        497..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        52
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000250|UniProtKB:Q21706"
FT   CARBOHYD        308
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   536 AA;  60621 MW;  ABE186D196789032 CRC64;
     MMLQTSTILQ LLLFLVGSVS AYNILVFSPA TSKSHLISNG RIADELARAG HNVTLLEIDF
     LGIVDTTKSA KLVKKTIVRT PKGMQGFRNV LQGFSEIVME DPGLWGLVEG NIMYQNAYNA
     LCEEFLEMDD IFQELKAQNF DGFFAEQLNI CGFGYAKALG IERRFLISSC PYFSHVYDYT
     SHPAPYASVP FVADMSPEPT YFERAQNLLN GFTCNMLFRY MHTRLSFIFR NKFGQDFPSV
     PEIVRNADII FLATDEIIDF SAPTLPNLVN IGGLGVDDDT TEMEPVFEAE MKKGEKGVIL
     FSLGTIANTS TIDKKVMESF LGIVKKFPDY HFLIRADKYD KNTKERAKGI SNVFVSDWLP
     QPAILHHPRL RTFITHAGYN GLVEAARAGV PLITIPFMFD QNLNSRAIEK KGWGIRSDKK
     KLLNDPDSFE ADLKEMLTNP SYTKNAHRIR DLIKSKPLGA RDRFIKTTEW VIQNGGVREL
     LTEGRDLSII SSYNLDIIVP VLFVLLYCLI IPFFKLIGGF YYYSCFGHIE SKHKLD