ID   UGT55_CAEEL             Reviewed;         512 AA.
AC   Q22180;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   11-APR-2003, sequence version 2.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Putative UDP-glucuronosyltransferase ugt-55;
DE            Short=UDPGT 55;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=ugt-55; Synonyms=ugt11; ORFNames=T04H1.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC         beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC         ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z78200; CAB01584.2; -; Genomic_DNA.
DR   PIR; T24477; T24477.
DR   RefSeq; NP_506073.2; NM_073672.4.
DR   AlphaFoldDB; Q22180; -.
DR   SMR; Q22180; -.
DR   STRING; 6239.T04H1.7; -.
DR   CAZy; GT1; Glycosyltransferase Family 1.
DR   PaxDb; Q22180; -.
DR   EnsemblMetazoa; T04H1.7.1; T04H1.7.1; WBGene00011452.
DR   GeneID; 188072; -.
DR   KEGG; cel:CELE_T04H1.7; -.
DR   UCSC; T04H1.7; c. elegans.
DR   CTD; 188072; -.
DR   WormBase; T04H1.7; CE31984; WBGene00011452; ugt-55.
DR   eggNOG; KOG1192; Eukaryota.
DR   GeneTree; ENSGT00970000196326; -.
DR   HOGENOM; CLU_012949_1_2_1; -.
DR   InParanoid; Q22180; -.
DR   OMA; YSPRMIP; -.
DR   OrthoDB; 508327at2759; -.
DR   PhylomeDB; Q22180; -.
DR   Reactome; R-CEL-1660662; Glycosphingolipid metabolism.
DR   Reactome; R-CEL-9753281; Paracetamol ADME.
DR   PRO; PR:Q22180; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00011452; Expressed in larva and 1 other tissue.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   InterPro; IPR035595; UDP_glycos_trans_CS.
DR   Pfam; PF00201; UDPGT; 1.
DR   PROSITE; PS00375; UDPGT; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Membrane; Reference proteome; Signal; Transferase;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..512
FT                   /note="Putative UDP-glucuronosyltransferase ugt-55"
FT                   /id="PRO_0000036051"
FT   TRANSMEM        487..507
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   512 AA;  58929 MW;  4CC3E9D107B548ED CRC64;
     MQLLTLPTLI FIFLNYGTPC LSLRILVYSP RMIPSHVAFV ANIANLLGQR GHNVVVVDNV
     LRSDISNKLD LKVIEKVVKV ETSANVAKLL ADQSIPINFW SMRNEPEEQK KVMKQLGIIF
     LEQCKYLVSK EETVFNELKH LEFDFGIHEV FDICGIGIFE KLGIRKSVIL SSTGMRDIVN
     EALGISSQLQ DASILSDYGN SIPFYGIRRN LKFHSAWRNF FEVQSKTLEP LFETTSSFEN
     LLRFSNLMFL NTHELADAHR PWSRRVHEIG GISFKFPMPL KNEYINLFNK YNSIILVSFG
     TTTPSFLMPE KYKNTLINTF QRFPDFLFIW KYEKDDEFTQ KNKKGNVVFK KFLPQVDLLE
     SRKIKLFITH GGQNSLLETF HSNTRTLITP LFGDQHRNAQ IALENGLSHV LLKDQLANEE
     LVYAAIKQGT ESNKKLDDNL LKLSSNLKNA KQTSENLFLD TVESTYTDNL SPLNFEFYPK
     LYSSDQILLY LDSIAMFTLT LLTMILIRKF LL