CA131_MOUSE
ID CA131_MOUSE Reviewed; 281 AA.
AC Q8CIL4; Q3UNZ3; Q9CZF4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Uncharacterized protein C1orf131 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Kidney;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-67, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Pancreas, and Spleen;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:Q8NDD1}.
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DR EMBL; AK012675; BAB28401.1; -; mRNA.
DR EMBL; AK143919; BAE25604.1; -; mRNA.
DR EMBL; BC023675; AAH23675.1; -; mRNA.
DR CCDS; CCDS22775.1; -.
DR RefSeq; NP_079891.2; NM_025615.2.
DR AlphaFoldDB; Q8CIL4; -.
DR SMR; Q8CIL4; -.
DR BioGRID; 211534; 2.
DR IntAct; Q8CIL4; 1.
DR MINT; Q8CIL4; -.
DR STRING; 10090.ENSMUSP00000034465; -.
DR iPTMnet; Q8CIL4; -.
DR PhosphoSitePlus; Q8CIL4; -.
DR EPD; Q8CIL4; -.
DR jPOST; Q8CIL4; -.
DR MaxQB; Q8CIL4; -.
DR PaxDb; Q8CIL4; -.
DR PeptideAtlas; Q8CIL4; -.
DR PRIDE; Q8CIL4; -.
DR Antibodypedia; 34684; 65 antibodies from 15 providers.
DR Ensembl; ENSMUST00000034465; ENSMUSP00000034465; ENSMUSG00000031984.
DR GeneID; 66523; -.
DR KEGG; mmu:66523; -.
DR UCSC; uc009nxs.2; mouse.
DR MGI; MGI:1913773; 2810004N23Rik.
DR VEuPathDB; HostDB:ENSMUSG00000031984; -.
DR eggNOG; ENOG502S2E3; Eukaryota.
DR GeneTree; ENSGT00390000017022; -.
DR HOGENOM; CLU_081604_0_0_1; -.
DR InParanoid; Q8CIL4; -.
DR OMA; EVVQFHS; -.
DR OrthoDB; 1536903at2759; -.
DR PhylomeDB; Q8CIL4; -.
DR TreeFam; TF328381; -.
DR BioGRID-ORCS; 66523; 23 hits in 75 CRISPR screens.
DR PRO; PR:Q8CIL4; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q8CIL4; protein.
DR Bgee; ENSMUSG00000031984; Expressed in ear vesicle and 247 other tissues.
DR Genevisible; Q8CIL4; MM.
DR GO; GO:0005694; C:chromosome; ISS:UniProtKB.
DR InterPro; IPR027973; DUF4602.
DR Pfam; PF15375; DUF4602; 1.
PE 1: Evidence at protein level;
KW Acetylation; Chromosome; Phosphoprotein; Reference proteome.
FT CHAIN 1..281
FT /note="Uncharacterized protein C1orf131 homolog"
FT /id="PRO_0000285030"
FT REGION 29..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 67
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 75
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDD1"
FT MOD_RES 172
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDD1"
FT MOD_RES 267
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDD1"
FT CONFLICT 5
FT /note="H -> T (in Ref. 1; BAB28401)"
FT /evidence="ECO:0000305"
FT CONFLICT 119
FT /note="E -> G (in Ref. 1; BAE25604)"
FT /evidence="ECO:0000305"
FT CONFLICT 182
FT /note="R -> Q (in Ref. 1; BAB28401)"
FT /evidence="ECO:0000305"
FT CONFLICT 251
FT /note="G -> V (in Ref. 1; BAB28401)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 281 AA; 31344 MW; 9EFAC62B06FD6FD8 CRC64;
MAAEHDSDSV EPPGSEALLD AVLRTLYDLG ETEGETEQKR IRKKKAKKRD SETIEDVAVE
PLPLPGSPVR GQKKSASSFF QKLREELQSA PAAPSEVPVT TAVSLSPPKN GSKLVEVVEF
QSKSKKRKLK SDEDEPAKNK TKVVKKDVDI QEFNLEKARL EVHRFGITGY GKGKERVLER
ERAIMLGAKP PKNTYVNYKV LQKQIKEKKI AVEEEKRAAR ETDIFKKKKK KGRGQEDRRS
KKSAPSILSS GQVGQVGKFR NGTLILSPTD IKKINSSRVA K
