UHPT_CHLPN
ID UHPT_CHLPN Reviewed; 455 AA.
AC Q9Z7N9; Q9JQ19;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 136.
DE RecName: Full=Probable hexose phosphate transport protein;
GN Name=uhpC; OrderedLocusNames=CPn_0665, CP_0082, CpB0691;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transport protein for sugar phosphate uptake. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. {ECO:0000305}.
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DR EMBL; AE001363; AAD18804.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF37968.1; -; Genomic_DNA.
DR EMBL; BA000008; BAA98872.1; -; Genomic_DNA.
DR EMBL; AE009440; AAP98620.1; -; Genomic_DNA.
DR PIR; A72050; A72050.
DR PIR; F86573; F86573.
DR RefSeq; NP_224861.1; NC_000922.1.
DR RefSeq; WP_010883303.1; NZ_LN847257.1.
DR AlphaFoldDB; Q9Z7N9; -.
DR SMR; Q9Z7N9; -.
DR STRING; 115711.CP_0082; -.
DR TCDB; 2.A.1.4.6; the major facilitator superfamily (mfs).
DR EnsemblBacteria; AAD18804; AAD18804; CPn_0665.
DR EnsemblBacteria; AAF37968; AAF37968; CP_0082.
DR GeneID; 45050716; -.
DR KEGG; cpa:CP_0082; -.
DR KEGG; cpj:uhpC; -.
DR KEGG; cpn:CPn_0665; -.
DR KEGG; cpt:CpB0691; -.
DR PATRIC; fig|115713.3.peg.735; -.
DR eggNOG; COG2271; Bacteria.
DR HOGENOM; CLU_001265_31_0_0; -.
DR OMA; AMPYLID; -.
DR OrthoDB; 1345431at2; -.
DR Proteomes; UP000000583; Chromosome.
DR Proteomes; UP000000801; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR021159; Sugar-P_transporter_CS.
DR InterPro; IPR000849; Sugar_P_transporter.
DR Pfam; PF07690; MFS_1; 1.
DR PIRSF; PIRSF002808; Hexose_phosphate_transp; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS00942; GLPT; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..455
FT /note="Probable hexose phosphate transport protein"
FT /id="PRO_0000199888"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 219..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 51659 MW; F6404E2F1F4CA076 CRC64;
MNVWTKFFQP PKHIKEIEDQ EVVKKKYKYW RIRIFYSMFI GYIFYYFTRK SFTFAMPTLI
ADLGFDKAQL GIIGSTLYFS YGISKFVSGV MSDQSNPRYF MAIGLMITGL TNIFFGMSSS
IVLFALWWGL NGWFQGWGWP PCARLLTHWY AKSERGTWWS VWSTSHNIGG ALIPILTGFI
IDYSGWRGAM YVPGILCIGM GLVLINRLRD TPQSLGLPPI EKYKRDPHHA HHEGKSASEG
TEEIERELST REILFTYVLT NQWLWFLAAA SFFIYIVRMA VNDWSALFLI ETKHYAAVKA
NFCVSLFEIG GLFGMLVAGW LSDKISKGNR GPMNVLFSLG LLFAILGMWF SRSHNQWWVD
GTLLFVIGFF LYGPQMMIGL AAAELSHKKA AGTASGFTGW FAYFGATFAG YPLGKVTDVW
GWKGFFIALL ACASIALLLF LPTWNATEKN TRSKA
