ID   UHPT_CHLTR              Reviewed;         456 AA.
AC   O84548;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Probable hexose phosphate transport protein;
GN   OrderedLocusNames=CT_544;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Transport protein for sugar phosphate uptake. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. {ECO:0000305}.
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DR   EMBL; AE001273; AAC68146.1; -; Genomic_DNA.
DR   PIR; A71501; A71501.
DR   RefSeq; NP_220059.1; NC_000117.1.
DR   RefSeq; WP_009871908.1; NC_000117.1.
DR   AlphaFoldDB; O84548; -.
DR   SMR; O84548; -.
DR   STRING; 813.O172_02995; -.
DR   EnsemblBacteria; AAC68146; AAC68146; CT_544.
DR   GeneID; 884321; -.
DR   KEGG; ctr:CT_544; -.
DR   PATRIC; fig|272561.5.peg.591; -.
DR   HOGENOM; CLU_001265_31_0_0; -.
DR   InParanoid; O84548; -.
DR   OMA; NAWFQGW; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0061513; F:glucose 6-phosphate:inorganic phosphate antiporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0015760; P:glucose-6-phosphate transport; IBA:GO_Central.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR021159; Sugar-P_transporter_CS.
DR   InterPro; IPR000849; Sugar_P_transporter.
DR   Pfam; PF07690; MFS_1; 1.
DR   PIRSF; PIRSF002808; Hexose_phosphate_transp; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS00942; GLPT; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..456
FT                   /note="Probable hexose phosphate transport protein"
FT                   /id="PRO_0000199889"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        421..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   456 AA;  51729 MW;  E443610D6B5B7F8F CRC64;
     MNLWTKIFQP PCHIKEISDP ELVKKQYKYW RMRIFYSMFL GYVFFYFTRK SFTFAMPTLI
     ADLGFDKAQL GIIGSTLYIT YGISKFVSGV MSDQSNPRYF MAIGLIITGI SNIFFGLSST
     IPLFVLFWGI NGWFQGWGWP PCARLLTHWY SKSERGTWWS VWSTSHNIGG ALIPVLTGVA
     IDYTGWRGAM FIPGIICIIM GFILIDRLRD TPQSLGLPAI EKFRKEEDAH PHEETTADIL
     EEEAERELST KEILFTYVLS NKWLWFLSFA SFFIYVVRMA VNDWSALYLI ETKDYSTVKA
     NLCVSLFEIG GLFGMLLAGW LSDTISKGKR GPMNVVFSLG LLVSILGLWG TRDYFVWWID
     GTFLFIIGFF LFGPQMMIGL AAAELSHKKA AGTASGFTGW FAYFGAAFAG YPLGKVAQDW
     GWHGFFVALL ACALIALILF LPTWNASEQS LRKHSH