UIDR_ECO57
ID UIDR_ECO57 Reviewed; 196 AA.
AC P0ACT8; P76892; P76895; Q59431;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=HTH-type transcriptional regulator UidR;
DE AltName: Full=Uid operon repressor;
GN Name=uidR; OrderedLocusNames=Z2623, ECs2326;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Repressor for the uidRABC (gusRABC) operon. {ECO:0000250}.
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DR EMBL; AE005174; AAG56607.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB35749.1; -; Genomic_DNA.
DR PIR; C85768; C85768.
DR PIR; F90919; F90919.
DR RefSeq; NP_310353.1; NC_002695.1.
DR RefSeq; WP_000969092.1; NZ_SWKA01000004.1.
DR AlphaFoldDB; P0ACT8; -.
DR SMR; P0ACT8; -.
DR STRING; 155864.EDL933_2572; -.
DR EnsemblBacteria; AAG56607; AAG56607; Z2623.
DR EnsemblBacteria; BAB35749; BAB35749; ECs_2326.
DR GeneID; 58389290; -.
DR GeneID; 913631; -.
DR KEGG; ece:Z2623; -.
DR KEGG; ecs:ECs_2326; -.
DR PATRIC; fig|386585.9.peg.2436; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_15_12_6; -.
DR OMA; AINHYFS; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF48498; SSF48498; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..196
FT /note="HTH-type transcriptional regulator UidR"
FT /id="PRO_0000070629"
FT DOMAIN 10..70
FT /note="HTH tetR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT DNA_BIND 33..52
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 196 AA; 21799 MW; 22912EF7695268D4 CRC64;
MMDNMQTEAQ PTRTRILNAA REIFSENGFH SASMKAICKS CAISPGTLYH HFISKEALIQ
AIILQDQERA LARFREPIEG IHFVDYMVES IVSLTHEAFG QRALVVEIMA EGMRNPQVAA
MLKNKHMTIT EFVAQRMRDA QQKGEISPDI NTAMTSRLLL DLTYGVLADI EAEDLAREAS
FAQGLRAMIG GILTAS
