ID   UIF_LITCT               Reviewed;         275 AA.
AC   C1C488;
DT   19-JAN-2010, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=UAP56-interacting factor;
DE   AltName: Full=Forty-two-three domain-containing protein 1;
DE            Short=Protein 40-2-3;
GN   Name=fyttd1; Synonyms=uif;
OS   Lithobates catesbeianus (American bullfrog) (Rana catesbeiana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX   NCBI_TaxID=8400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Helbing C.C., Veldhoen N., Leong J., Koop B.F.;
RT   "Rana catesbeiana ESTs and full-length cDNAs.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for mRNA export from the nucleus to the cytoplasm.
CC       Acts as an adapter that uses the ddx39b/uap56-nfx1 pathway to ensure
CC       efficient mRNA export and delivering to the nuclear pore (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}. Nucleus
CC       speckle {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UIF family. {ECO:0000305}.
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DR   EMBL; BT081667; ACO51798.1; -; mRNA.
DR   AlphaFoldDB; C1C488; -.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; ISS:UniProtKB.
DR   InterPro; IPR009782; FYTTD1.
DR   PANTHER; PTHR21038; PTHR21038; 1.
PE   2: Evidence at transcript level;
KW   mRNA transport; Nucleus; RNA-binding; Transport.
FT   CHAIN           1..275
FT                   /note="UAP56-interacting factor"
FT                   /id="PRO_0000390997"
FT   MOTIF           11..29
FT                   /note="UAP56-binding motif"
SQ   SEQUENCE   275 AA;  31358 MW;  27B2D1AA3DFA8E37 CRC64;
     MVPQTANMNE VIDKIDMSLD DIIKLNKEQQ NKATFNGGAR TNSFQWFQNK WGSRQATDNG
     IQGRKNGMFG VKTGLALRKM NSWKGVSPLN RPPLSLRNSE GQWSPFRRRT NLSRRLGFVP
     SLKRNYFHSS YAQASTFRRG LRTNQQRDQR QATYFQKRGL KVQATMDMEQ LEEFPELKRA
     HPWRTSMNSG GILTVSIDNP TAALLPSTRL PRPTLPFLLK KEGSEPKIPK GVPLDFDINS
     VVKQTGITLN ERFKILKEQR LSQSMSKGSR FVTVG