ID   UIF_XENLA               Reviewed;         288 AA.
AC   Q4V7Q7;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=UAP56-interacting factor;
DE   AltName: Full=Forty-two-three domain-containing protein 1;
DE            Short=Protein 40-2-3;
GN   Name=fyttd1; Synonyms=uif;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for mRNA export from the nucleus to the cytoplasm.
CC       Acts as an adapter that uses the ddx39b/uap56-nfx1 pathway to ensure
CC       efficient mRNA export and delivering to the nuclear pore (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}. Nucleus
CC       speckle {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UIF family. {ECO:0000305}.
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DR   EMBL; BC097769; AAH97769.1; -; mRNA.
DR   RefSeq; NP_001089514.1; NM_001096045.1.
DR   AlphaFoldDB; Q4V7Q7; -.
DR   DNASU; 734567; -.
DR   GeneID; 734567; -.
DR   KEGG; xla:734567; -.
DR   CTD; 734567; -.
DR   Xenbase; XB-GENE-1015374; fyttd1.S.
DR   OMA; QNRAQQF; -.
DR   OrthoDB; 1377721at2759; -.
DR   Proteomes; UP000186698; Chromosome 5S.
DR   Bgee; 734567; Expressed in blastula and 19 other tissues.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; ISS:UniProtKB.
DR   InterPro; IPR009782; FYTTD1.
DR   PANTHER; PTHR21038; PTHR21038; 1.
PE   2: Evidence at transcript level;
KW   mRNA transport; Nucleus; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..288
FT                   /note="UAP56-interacting factor"
FT                   /id="PRO_0000287444"
FT   REGION          183..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           11..29
FT                   /note="UAP56-binding motif"
SQ   SEQUENCE   288 AA;  32341 MW;  EFE5100366BA5081 CRC64;
     MAPLKTSVSD TIDKIDMSLD DIIKLNKQEQ NRKQLKGRYN GSFRQFRNSW GRWGAQHTSG
     AGNNLRSQGL RKRPYGVKTG LAMRKMASWK GISPLNHQPL VRNSPGQLVS FRKRLNPQRS
     PDSGVKTSSS LQRYYLRSSS YAPTNTFRSG FRMDQQRETR QATFLSRRGL KVQTLMDMDQ
     HLDLPELSKT PPWRTSVSSG GSLTVSIDNP SAVTLPSSLG SRLPRPPFPF LTKKEGSETK
     VPKGVPLEFD INSVAKQSGI TLNERFKILK EQRLAQAFTK GSRFVTVG