ID   UIF_XENTR               Reviewed;         289 AA.
AC   Q28IB3; B5DFP2;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=UAP56-interacting factor;
DE   AltName: Full=Forty-two-three domain-containing protein 1;
DE            Short=Protein 40-2-3;
GN   Name=fyttd1; Synonyms=uif; ORFNames=TEgg012o15.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Oviduct;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for mRNA export from the nucleus to the cytoplasm.
CC       Acts as an adapter that uses the ddx39b/uap56-nfx1 pathway to ensure
CC       efficient mRNA export and delivering to the nuclear pore (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}. Nucleus
CC       speckle {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UIF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR760495; CAJ81824.1; -; mRNA.
DR   EMBL; BC169138; AAI69138.1; -; mRNA.
DR   RefSeq; NP_001037957.1; NM_001044492.1.
DR   AlphaFoldDB; Q28IB3; -.
DR   STRING; 8364.ENSXETP00000029814; -.
DR   PaxDb; Q28IB3; -.
DR   GeneID; 733719; -.
DR   KEGG; xtr:733719; -.
DR   CTD; 84248; -.
DR   Xenbase; XB-GENE-1015369; fyttd1.
DR   eggNOG; ENOG502QWD4; Eukaryota.
DR   HOGENOM; CLU_076911_0_0_1; -.
DR   InParanoid; Q28IB3; -.
DR   OrthoDB; 1377721at2759; -.
DR   TreeFam; TF336232; -.
DR   Reactome; R-XTR-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR   Reactome; R-XTR-72187; mRNA 3'-end processing.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; ISS:UniProtKB.
DR   InterPro; IPR009782; FYTTD1.
DR   PANTHER; PTHR21038; PTHR21038; 1.
PE   2: Evidence at transcript level;
KW   mRNA transport; Nucleus; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..289
FT                   /note="UAP56-interacting factor"
FT                   /id="PRO_0000287445"
FT   REGION          213..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           11..29
FT                   /note="UAP56-binding motif"
FT   CONFLICT        18
FT                   /note="L -> S (in Ref. 2; AAI69138)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        283
FT                   /note="N -> S (in Ref. 2; AAI69138)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   289 AA;  32598 MW;  20D3F6041E478D54 CRC64;
     MAPLKTSVPD TMDKIDMLLD DIIKLNKQEQ NRNQLKGRYN GSFRQFRNSW GRWGAQRTSG
     AGNTLRSQGL KKRTYGVKTG LAMRKMASWK GTSPLNRPPL SVRNSPGQLV SFRKRMNLQR
     SPDFGVKTSS SLQRYYLRSS SYAQTNTFRS GFRMDQQRET RQATFLSRRG LKVQTLMDMD
     QHLDLPELSR TPPWRTSVSS GGTLTVSIDN PSAVTSSSSL GSRLPRPPFP FLTKKEGSET
     KVPKGVPLEF DINSVAKQTG ITLNERFKIL KEQRLAQAFT KGNRFVTVG