ID   UL05_HCMVM              Reviewed;         166 AA.
AC   Q6SWC5; D2K3H5;
DT   11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Protein UL5;
GN   Name=UL5;
OS   Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=295027;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
CC   -!- FUNCTION: May play a role in rearrangement of cellular cytoskeleton
CC       towards an efficient viral assembly and spreading.
CC       {ECO:0000250|UniProtKB:P16776}.
CC   -!- SUBUNIT: Interacts with host IQGAP1. {ECO:0000250|UniProtKB:P16776}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250|UniProtKB:P16776}.
CC       Note=Localizes within the assembly compartments within host cytoplasm,
CC       but is not incorporated in the virion. {ECO:0000250|UniProtKB:P16776}.
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DR   EMBL; AY446894; AAR31571.1; -; Genomic_DNA.
DR   RefSeq; YP_081465.1; NC_006273.2.
DR   PRIDE; Q6SWC5; -.
DR   DNASU; 3077425; -.
DR   GeneID; 3077425; -.
DR   KEGG; vg:3077425; -.
DR   Reactome; R-HSA-9609690; HCMV Early Events.
DR   Proteomes; UP000000938; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR016497; Herpes_UL5.
DR   PIRSF; PIRSF006846; UCP006846_UL5; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host-virus interaction; Reference proteome.
FT   CHAIN           1..166
FT                   /note="Protein UL5"
FT                   /id="PRO_0000418274"
SQ   SEQUENCE   166 AA;  18927 MW;  7966BD2400DB800B CRC64;
     MFLGYSDCVD PGLAVYRVSR SRLKLMLSFV WLVGLRFHDC AAFESCCYDI TEAESNKAIS
     RDEAAFTSSV STRTPSLAIA PPPDRSMLLS REEELVPWSR LIITKQFYGG LIFHTTWVTG
     FVLLGLLTLF ASLFRVPQSI CRFCIDRLRD IARPLKYRYQ RLVATV