ID   UL136_HCMVM             Reviewed;         240 AA.
AC   F5HF35;
DT   13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   23-FEB-2022, entry version 24.
DE   RecName: Full=Protein UL136;
GN   Name=UL136;
OS   Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=295027;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
RN   [2]
RP   SUBCELLULAR LOCATION, AND INTERACTION WITH HOST ATP1B1.
RC   STRAIN=H;
RX   PubMed=22030864; DOI=10.1590/s0100-879x2011007500144;
RA   Cui X., Sun Z.R., Ren G.W., Wang G.L., Qi Y., Ma Y.P., Ruan Q.;
RT   "Interaction between human cytomegalovirus UL136 protein and ATP1B1
RT   protein.";
RL   Braz. J. Med. Biol. Res. 44:1251-1255(2011).
CC   -!- SUBUNIT: Interacts with host ATP1B1. {ECO:0000269|PubMed:22030864}.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000269|PubMed:22030864};
CC       Single-pass membrane protein {ECO:0000269|PubMed:22030864}.
CC   -!- SIMILARITY: Belongs to the HHV-5 UL136 protein family. {ECO:0000305}.
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DR   EMBL; AY446894; AAR31683.1; -; Genomic_DNA.
DR   RefSeq; YP_081579.1; NC_006273.2.
DR   PRIDE; F5HF35; -.
DR   DNASU; 3077568; -.
DR   GeneID; 3077568; -.
DR   KEGG; vg:3077568; -.
DR   Proteomes; UP000000938; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Host membrane; Host-virus interaction; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..240
FT                   /note="Protein UL136"
FT                   /id="PRO_0000417857"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          119..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          164..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   240 AA;  27060 MW;  3A21408C8F2E29D2 CRC64;
     MSVKGVEMPE MTWDLDVGNK WRRRKVLSRI HRFWECRLRV WWLSDAGVRE TDPPRPRRRP
     TWMTAVFHVI CAVLLTLMIM AIGALIAYLR YYHQDSWRDM LHDLFCGCHY PEKCRRHHER
     QRSRRRAMDV PDPELGDPAR RPLNGAMYYG SGCRFDTVEM VDETRPAPPA LSSPETGDDS
     NDDAVAGGGA GGVTSSATRT TSSNALLPEW MDAVHVAVQA AVQATVQVSG PRENAVSPAT