UL136_HCMVT
ID UL136_HCMVT Reviewed; 240 AA.
AC Q6SWN0;
DT 13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 1.
DT 23-FEB-2022, entry version 21.
DE RecName: Full=Protein UL136;
GN Name=UL136;
OS Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX NCBI_TaxID=10363;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT "Genetic content of wild-type human cytomegalovirus.";
RL J. Gen. Virol. 85:1301-1312(2004).
CC -!- SUBUNIT: Interacts with host ATP1B1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HHV-5 UL136 protein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FJ616285; AAR31466.1; -; Genomic_DNA.
DR Proteomes; UP000006907; Genome.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Host membrane; Host-virus interaction; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..240
FT /note="Protein UL136"
FT /id="PRO_0000417858"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 119..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 240 AA; 27121 MW; B5D921F464BEA366 CRC64;
MSVKGVEMPE MTWDLDVGNK WRRRKALSRI HRFWECRLRV WWLSDAGVRE TDPPRPRRRP
TWMTAVFHVI CAVLLTLMIM AIGALIAYLR YYHQDSWRDM LHDLFCGCHY PEKCRRHHER
QRRRRRAMDV PDPELGDPAR RPLNGAMYYG SGCRFDTVEM VDETRPAPPA LSSPETGDDS
NDDAVAGGGA GGVTSPATRT TSPNALLPEW MDAVHVAVQA AVQATVQVSG PRENAVSPAT