UL139_HCMVM
ID UL139_HCMVM Reviewed; 138 AA.
AC Q6SW14; D2K3T7;
DT 11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 02-JUN-2021, entry version 38.
DE RecName: Full=Membrane glycoprotein UL139;
DE Flags: Precursor;
GN Name=UL139;
OS Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX NCBI_TaxID=295027;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT "Genetic content of wild-type human cytomegalovirus.";
RL J. Gen. Virol. 85:1301-1312(2004).
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AY446894; AAR31681.1; -; Genomic_DNA.
DR RefSeq; YP_081577.1; NC_006273.2.
DR DNASU; 3077570; -.
DR GeneID; 3077570; -.
DR KEGG; vg:3077570; -.
DR Proteomes; UP000000938; Genome.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR021042; Herpes_UL139_cytomegalovirus.
DR Pfam; PF12507; HCMV_UL139; 1.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..15
FT /evidence="ECO:0000255"
FT CHAIN 16..138
FT /note="Membrane glycoprotein UL139"
FT /id="PRO_0000418302"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 17..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 138 AA; 14088 MW; 569C7706B7F3B3AF CRC64;
MLWILVLFAL AASASETTTG TSSNSSQSTS AGTTNTTTPS TACINASNGS DLGAPQLALL
AASGWTLSGL LLIFTCCLCC FWLVRKVCSC CGNSSESESK ATHAYTNAAF TSSDATLPMG
TTGSYTPPQD GSFPPPPR