ID   UL24_EBVB9              Reviewed;         248 AA.
AC   P03232; Q777B8;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Protein UL24 homolog;
GN   ORFNames=BXRF1;
OS   Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10377;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6092825;
RA   Bankier A.T., Deininger P.L., Farrell P.J., Barrell B.G.;
RT   "Sequence analysis of the 17,166 base-pair EcoRI fragment C of B95-8
RT   Epstein-Barr virus.";
RL   Mol. Biol. Med. 1:21-45(1983).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6087149; DOI=10.1038/310207a0;
RA   Baer R., Bankier A.T., Biggin M.D., Deininger P.L., Farrell P.J.,
RA   Gibson T.J., Hatfull G., Hudson G.S., Satchwell S.C., Seguin C.,
RA   Tuffnell P.S., Barrell B.G.;
RT   "DNA sequence and expression of the B95-8 Epstein-Barr virus genome.";
RL   Nature 310:207-211(1984).
CC   -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC       role in the dispersal of several host nucleolar proteins including
CC       NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC       impact on nuclear egress, UL24 supposedly acts on this process through
CC       its effect on host nucleoli. {ECO:0000250|UniProtKB:P10208}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P10208}. Host
CC       cytoplasm {ECO:0000250|UniProtKB:P10208}. Host nucleus, host nucleolus
CC       {ECO:0000250|UniProtKB:P10208}. Host Golgi apparatus
CC       {ECO:0000250|UniProtKB:P10208}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR   EMBL; V01555; CAA24798.1; -; Genomic_DNA.
DR   EMBL; AJ507799; CAD53452.1; -; Genomic_DNA.
DR   PIR; A03796; QQBE1R.
DR   RefSeq; YP_401702.1; NC_007605.1.
DR   IntAct; P03232; 3.
DR   MINT; P03232; -.
DR   PRIDE; P03232; -.
DR   DNASU; 3783743; -.
DR   GeneID; 3783743; -.
DR   KEGG; vg:3783743; -.
DR   Proteomes; UP000153037; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..248
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000115990"
FT   REGION          194..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  27062 MW;  E839C7D8E47E7CAE CRC64;
     MDPTRGLCAL STHDLAKFHS LPPARKAAGK RAHLRCYSKL LSLKSWEQLA SFLSLPPGPT
     FTDFRLFFEV TLGRRIADCV VVALQPYPRC YIVEFKTAMS NTANPQSVTR KAQRLEGTAQ
     LCDCANFLRT SCPPVLGSQG LEVLAALVFK NQRSLRTLQV EFPALGQKTL PTSTTGLLNL
     LSRWQDGALR ARLDRPRPTA QGHRPRTHVG PKPSQLTARV PRSARAGRAG GRKGQVGAVG
     QVCPGAQK