UL24_EHV1B
ID UL24_EHV1B Reviewed; 272 AA.
AC P28927; Q6DLH3;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 23-FEB-2022, entry version 64.
DE RecName: Full=Protein UL24 homolog;
GN Name=UL24; OrderedLocusNames=37;
OS Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX NCBI_TaxID=31520;
OH NCBI_TaxID=9796; Equus caballus (Horse).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT "The DNA sequence of equine herpesvirus-1.";
RL Virology 189:304-316(1992).
CC -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC role in the dispersal of several host nucleolar proteins including
CC NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC impact on nuclear egress, UL24 supposedly acts on this process through
CC its effect on host nucleoli (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm
CC {ECO:0000250}. Host nucleus, host nucleolus {ECO:0000250}. Host Golgi
CC apparatus {ECO:0000250}.
CC -!- INDUCTION: Expressed late in the infection cycle.
CC -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR EMBL; AY665713; AAT67295.1; -; Genomic_DNA.
DR PIR; C36799; WZBED1.
DR RefSeq; YP_053083.1; NC_001491.2.
DR GeneID; 1487532; -.
DR KEGG; vg:1487532; -.
DR Proteomes; UP000001189; Genome.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR InterPro; IPR002580; Herpes_UL24.
DR Pfam; PF01646; Herpes_UL24; 1.
PE 2: Evidence at transcript level;
KW Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein;
KW Reference proteome; Virion.
FT CHAIN 1..272
FT /note="Protein UL24 homolog"
FT /id="PRO_0000115980"
SQ SEQUENCE 272 AA; 29188 MW; AA6EA241F18B1C88 CRC64;
MKRRQRLTAR SRLRAGIRCH NRFYNAMVQD LASAKRNGVY GERLAPLFSE LVPAETLKTA
LGVSLAFEVN LGQRRPDCVC TVQFGKGSDA KGVCILIELK TCRFSKNMNT ASKNLQRKGG
MRQLHDSCRL LARTLPPGSG EIVLAPVLVF VAQRGMRVLR VTRLSPQVVY SNAAVLSCTI
SRLAEYAPPV SAKSTRRRCV AKGTKAKAFS TKAAAEPVPS ITPAQPSAAA AVVSLFPAAV
PANTTNAAAV HQPVAVSHVN PLAWAASLFS PK