ID   UL24_EHV4               Reviewed;         272 AA.
AC   P24432;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   23-FEB-2022, entry version 54.
DE   RecName: Full=Protein UL24 homolog;
GN   Name=UL24;
OS   Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=10333;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2391500; DOI=10.1099/0022-1317-71-8-1801;
RA   Nicolson L., Cullinane A.A., Onions D.E.;
RT   "The nucleotide sequence of the equine herpesvirus 4 thymidine kinase
RT   gene.";
RL   J. Gen. Virol. 71:1801-1805(1990).
CC   -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC       role in the dispersal of several host nucleolar proteins including
CC       NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC       impact on nuclear egress, UL24 supposedly acts on this process through
CC       its effect on host nucleoli (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus, host nucleolus {ECO:0000250}. Host Golgi
CC       apparatus {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR   EMBL; D14486; BAA03377.1; -; Genomic_DNA.
DR   PIR; T42581; T42581.
DR   RefSeq; NP_045255.1; NC_001844.1.
DR   GeneID; 1487603; -.
DR   KEGG; vg:1487603; -.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein; Virion.
FT   CHAIN           1..272
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000115982"
SQ   SEQUENCE   272 AA;  29492 MW;  941724188C7611D6 CRC64;
     MKRKQRLTAR SRLRAGIRCH NRFYNAMVQD LASAKKNGVY GARLAPLFSE LVPAETLKTA
     MGVSLAFEVN LGQRRPDCVC TVQFGHGSDA KGVCILIELK TCRFSKNMNT ASKNLQRKGG
     MRQLHDSCRL LAKTLPPGSG EILLAPVLVF VAQRGMRVLR VTRLSPQVVY SNAAVLSCTI
     SRLAEYSPPI SERSTRRRCV TRRTNSKAFR AKTTTGSIQP ITQAKPAATA AVASLFSATA
     QANTTNAAVG YQPATISLAN PLAWVASLFA PK