ID   UL24_GAHVM              Reviewed;         304 AA.
AC   Q9E6P4;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   12-AUG-2020, entry version 49.
DE   RecName: Full=Protein UL24 homolog;
GN   Name=MDV035;
OS   Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's
OS   disease herpesvirus type 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus.
OX   NCBI_TaxID=10389;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10933706; DOI=10.1128/jvi.74.17.7980-7988.2000;
RA   Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., Kutish G.F.;
RT   "The genome of a very virulent Marek's disease virus.";
RL   J. Virol. 74:7980-7988(2000).
CC   -!- FUNCTION: May play a role in the dispersal of host nucleolin from the
CC       nucleolus throughout the nucleus leading to a decrease in ribosome
CC       biogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus. Host Golgi
CC       apparatus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HHV-1 UL24 protein family. {ECO:0000305}.
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DR   EMBL; AF243438; AAG14215.1; -; Genomic_DNA.
DR   RefSeq; YP_001033952.1; NC_002229.3.
DR   GeneID; 4811498; -.
DR   KEGG; vg:4811498; -.
DR   Proteomes; UP000008072; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039592; P:suppression by virus of G2/M transition of host mitotic cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host G2/M cell cycle arrest by virus; Host Golgi apparatus;
KW   Host nucleus; Host-virus interaction;
KW   Modulation of host cell cycle by virus; Reference proteome.
FT   CHAIN           1..304
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000406546"
SQ   SEQUENCE   304 AA;  34920 MW;  04AAE574407556E7 CRC64;
     MSSEMPLPTT IVAPTCSMGE KNVLKRYRRQ VSSTRNFKRH VNTNVLRKRR LAAGVRCHDR
     FYKRLYAEAM CLGSQVYDWP GRSFAKIFGK VMVLDVFKQL TDFRLVFEVN LERRRPDCIC
     MFKLPRDLWE VGCDGVCVIL ELKTCKFSRN LKTRSKHEQR LTGIKQLLDS KSLIGQIAPQ
     GSDCIVICPM LVFVARRKLS VLHVMCLKKR HIVTDFHRLC SILATASDYK ARITDTHKIL
     KRHNTNTIHI QRRSGKASAN VTDLRNHIAC NKTATLSFSN NQERTGGTAM RNMANIIARL
     VQRP