ID   UL24_HHV7J              Reviewed;         239 AA.
AC   P52386;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Protein UL24 homolog;
GN   Name=U49;
OS   Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=57278;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8709220; DOI=10.1128/jvi.70.9.5975-5989.1996;
RA   Nicholas J.;
RT   "Determination and analysis of the complete nucleotide sequence of human
RT   herpesvirus.";
RL   J. Virol. 70:5975-5989(1996).
CC   -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC       role in the dispersal of several host nucleolar proteins including
CC       NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC       impact on nuclear egress, UL24 supposedly acts on this process through
CC       its effect on host nucleoli (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus, host nucleolus {ECO:0000250}. Host Golgi
CC       apparatus {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR   EMBL; U43400; AAC54711.1; -; Genomic_DNA.
DR   PIR; T41951; T41951.
DR   RefSeq; YP_073789.1; NC_001716.2.
DR   PRIDE; P52386; -.
DR   DNASU; 3289507; -.
DR   GeneID; 3289507; -.
DR   KEGG; vg:3289507; -.
DR   Proteomes; UP000009246; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..239
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000115987"
FT   REGION          212..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..233
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   239 AA;  28569 MW;  F4EBC038679BE6B0 CRC64;
     MSLEYLPPVR RRIGQYNHLR IYKKILLLKS NFEKLNFFLG NLFPEELHDS KIHVYFEVRL
     GCRIPDCIIV FRHFGEKLLK TFHCYFFEFK TTFAKSNLFS IQKNRTQKIQ YLQGLRQLRQ
     ATDYLQQFVI KNESLCKVNP VICFFRQHGL KLDFVKTFIA KELQLSSTFL CNLFTKYQND
     TVKSILSISN PTNFRRACQK YSNLYRGRYA TTPKLGNSKT SKRKRRNSKK QDFKKLVKN