ID   UL24_ILTVT              Reviewed;         287 AA.
AC   P23986;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   29-SEP-2021, entry version 53.
DE   RecName: Full=Protein UL24 homolog;
DE   AltName: Full=ORF 3;
OS   Infectious laryngotracheitis virus (strain Thorne V882) (ILTV) (Gallid
OS   herpesvirus 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Iltovirus.
OX   NCBI_TaxID=10344;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2157797; DOI=10.1099/0022-1317-71-4-841;
RA   Griffin A.M., Boursnell M.E.;
RT   "Analysis of the nucleotide sequence of DNA from the region of the
RT   thymidine kinase gene of infectious laryngotracheitis virus; potential
RT   evolutionary relationships between the herpesvirus subfamilies.";
RL   J. Gen. Virol. 71:841-850(1990).
CC   -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC       role in the dispersal of several host nucleolar proteins including
CC       NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC       impact on nuclear egress, UL24 supposedly acts on this process through
CC       its effect on host nucleoli (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus, host nucleolus {ECO:0000250}. Host Golgi
CC       apparatus {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR   EMBL; D00565; BAA00441.1; -; Genomic_DNA.
DR   PIR; C43675; C43675.
DR   RefSeq; YP_182353.1; NC_006623.1.
DR   GeneID; 3239036; -.
DR   KEGG; vg:3239036; -.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein; Virion.
FT   CHAIN           1..287
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000115991"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          254..287
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..33
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   287 AA;  32149 MW;  492E1599D08C6175 CRC64;
     MARRRKEVQR GESRSHRSRT RSKTAHHRKF SRRQLRPSLR ARLNAGIRCH NRFYRALVRS
     LEEVFEGGGD GRLAYTIIPQ CKPAGGKIVV MFEVNLGLRK PDCICLLETQ HEMKCIVIEL
     KTCRFSKSLM TESKLRQGYT GTLQLRDSAR LLENLAVPGT EKVKILSLLV FVAQRGMNIL
     AVKTVGETVI NVSSELFFVT LATRSQYLKT FCAKLEPRVS HARSKYQQES AKNADLASPA
     PSALQTVAAL FSSRVGKESA TKPASYSTST EESKNLSEPC FDPDSNL