UL24_PSHV1
ID UL24_PSHV1 Reviewed; 318 AA.
AC Q6UDK8;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 23-FEB-2022, entry version 40.
DE RecName: Full=Protein UL24;
GN Name=UL24;
OS Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1)
OS (Pacheco's disease virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Iltovirus.
OX NCBI_TaxID=670426;
OH NCBI_TaxID=152276; Amazona oratrix (yellow-headed parrot).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16873243; DOI=10.1128/jvi.00134-06;
RA Thureen D.R., Keeler C.L. Jr.;
RT "Psittacid herpesvirus 1 and infectious laryngotracheitis virus:
RT Comparative genome sequence analysis of two avian alphaherpesviruses.";
RL J. Virol. 80:7863-7872(2006).
CC -!- FUNCTION: May play a role in the dispersal of host nucleolin from the
CC nucleolus throughout the nucleus leading to a decrease in ribosome
CC biogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus. Host Golgi
CC apparatus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HHV-1 UL24 protein family. {ECO:0000305}.
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DR EMBL; AY372243; AAQ73702.1; -; Genomic_DNA.
DR RefSeq; NP_944396.1; NC_005264.1.
DR PRIDE; Q6UDK8; -.
DR GeneID; 2656982; -.
DR KEGG; vg:2656982; -.
DR Proteomes; UP000006840; Genome.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0039592; P:suppression by virus of G2/M transition of host mitotic cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR002580; Herpes_UL24.
DR Pfam; PF01646; Herpes_UL24; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host G2/M cell cycle arrest by virus; Host Golgi apparatus;
KW Host nucleus; Host-virus interaction;
KW Modulation of host cell cycle by virus; Reference proteome.
FT CHAIN 1..318
FT /note="Protein UL24"
FT /id="PRO_0000406848"
FT REGION 258..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..290
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 34384 MW; 4E3C51E1B40FB1F7 CRC64;
MPRRRRGPRC DPSSALAVDV AAAVAAATSR TRAQKVRKAK KVLAANGHKW HRRAKTPVNK
RTLVAARLLA GVRCHNRFYG ALVSSFETAY CMNHRHGSDG LAATIIAEAC GAVPVCSLNT
TIMFEVNLGG RRPDCICVLD RAGVAGAPRE SVCLIVELKT CRFSRSALTE SKKNQYATGL
RQLRDSAKII CDVAVPGADF VHIVPVLVFV AQRSMRIMDV RKFNERVVRA NAELLRLRLA
ALGVYSRSFA AAPQRLQSAQ DRCHDHAATP KPTPAVVPSP PAPPNPAPPQ SRVGFGSALA
MATAVMLGEY ARENKPPR