ID   UL24_SHV21              Reviewed;         303 AA.
AC   Q01005;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   29-SEP-2021, entry version 49.
DE   RecName: Full=Protein UL24 homolog;
GN   Name=20;
OS   Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus.
OX   NCBI_TaxID=10383;
OH   NCBI_TaxID=9521; Saimiri sciureus (Common squirrel monkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1321287; DOI=10.1128/jvi.66.8.5047-5058.1992;
RA   Albrecht J.-C., Nicholas J., Biller D., Cameron K.R., Biesinger B.,
RA   Newman C., Wittmann S., Craxton M.A., Coleman H., Fleckenstein B.,
RA   Honess R.W.;
RT   "Primary structure of the herpesvirus saimiri genome.";
RL   J. Virol. 66:5047-5058(1992).
CC   -!- FUNCTION: May participate in nuclear egress of viral particles. Plays a
CC       role in the dispersal of several host nucleolar proteins including
CC       NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively
CC       impact on nuclear egress, UL24 supposedly acts on this process through
CC       its effect on host nucleoli (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus, host nucleolus {ECO:0000250}. Host Golgi
CC       apparatus {ECO:0000250}.
CC   -!- INDUCTION: Expressed late in the infection cycle.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL24 family. {ECO:0000305}.
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DR   EMBL; X64346; CAA45644.1; -; Genomic_DNA.
DR   RefSeq; NP_040222.1; NC_001350.1.
DR   PRIDE; Q01005; -.
DR   GeneID; 1682502; -.
DR   KEGG; vg:1682502; -.
DR   Proteomes; UP000000587; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002580; Herpes_UL24.
DR   Pfam; PF01646; Herpes_UL24; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host Golgi apparatus; Host nucleus; Late protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..303
FT                   /note="Protein UL24 homolog"
FT                   /id="PRO_0000115989"
FT   REGION          235..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..276
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  34943 MW;  DF6D59F7A1C83A0B CRC64;
     MLSVIKQRDK EVLAHLPNKR KIAGNKAHLE TYKKLAKYTV SASIFKFLSI SHPCPLRAKT
     RLFFEVSLGN RIADCVMLTS CGETRICYVI ELKTCMTSNL DLISDIRKSQ RSQGLCQLAD
     TVNFIHNYAP LGRQAWTVLP ILIFKSQKTL KTLHIETPKF PVNLTHTSEE KLSCFLWSRA
     DVEIRKKIHL APKPKRIFKW DSLLDSTSTE HSAYRQKLIE RNKKKCFTLQ NQTSKFRDRT
     NKKSNDQLRA RQANARPCKK KQHNNKRLRN NRKHGGKVSR LTTTTSFSSE AAFSNYPVST
     HKL