ID   UL32_GAHVM              Reviewed;         641 AA.
AC   Q9E6N7;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Packaging protein UL32 homolog;
GN   Name=MDV046;
OS   Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's
OS   disease herpesvirus type 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus.
OX   NCBI_TaxID=10389;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10933706; DOI=10.1128/jvi.74.17.7980-7988.2000;
RA   Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., Kutish G.F.;
RT   "The genome of a very virulent Marek's disease virus.";
RL   J. Virol. 74:7980-7988(2000).
CC   -!- FUNCTION: Plays a role in efficient localization of neo-synthesized
CC       capsids to nuclear replication compartments, thereby controlling
CC       cleavage and packaging of virus genomic DNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL32 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF243438; AAG14226.1; -; Genomic_DNA.
DR   RefSeq; YP_001033961.1; NC_002229.3.
DR   GeneID; 4811506; -.
DR   KEGG; vg:4811506; -.
DR   Proteomes; UP000008072; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR002597; Herpes_env.
DR   Pfam; PF01673; Herpes_env; 1.
DR   PROSITE; PS51988; HERPESVIRUS_UL32; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host nucleus; Metal-binding; Reference proteome; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..641
FT                   /note="Packaging protein UL32 homolog"
FT                   /id="PRO_0000406526"
FT   REGION          101..187
FT                   /note="Zinc finger 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   REGION          467..547
FT                   /note="Zinc finger 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         101
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         104
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         181
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         187
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         467
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         470
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         540
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
FT   BINDING         547
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01332"
SQ   SEQUENCE   641 AA;  71550 MW;  28AE9F7CFFF0DCA6 CRC64;
     MANRPTELAA FIRSSGEADG WIEESFKEPY VAFNPDVLMY NDTLFNELLL SAHALKINSI
     QDVQSDDTVE DAGDIGNEVI HSELVTFIET AADVYALDRQ CLVCRVLDMY RRNFGLSALW
     MADYAFLCSK CLGSPPCATA TFIAAFEFVY IMDKHFLSDH GCTLVRSFGK KLLTLEDIQR
     HFFLHGCFRT DGGVPGRRHD EVITSRSKQG RLVGRRGKFS TAGDAKVLYS NYSYLAQSAT
     RALLMTLSDL GSAPLEVIEG RQKSISGDVR NELRDGIESR KRVAHVIHSV GPVHSCPTTL
     SVALAGWKDC AKNVECNFFQ LESCTLRASS EDNDYEHEWE LRASEEKLNV VENVQDMQQI
     DASQCEHHEH ARNEDCTMGY GNLVLLLLAG TGSAPEAASE LAFMAAKVRR ETVDIFWKNH
     RREFANDVTA AYSACYGEDS EPDLELGPLM ITQLKHAITK GGTSAECLLC NLLLIRTYWL
     AMRKFKRDII TYSANNIGLF HSIEPVLDAW RSQGHRTDLG DEGCFVTLMK SAGTEAIYKH
     LFCDPMCAAR IAQTNPRSLF DHPDATNHDE LALYKARLAS QNHFEGRVCA GLWALAYTFK
     TYQVFPPRPT ALSAFVKDAG ALLQRHSISL ISLEHTLGVY V