UL41A_HCMVA
ID UL41A_HCMVA Reviewed; 78 AA.
AC O39920; Q7M6P2;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 23-FEB-2022, entry version 69.
DE RecName: Full=Protein UL41A;
GN Name=UL41A;
OS Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX NCBI_TaxID=10360;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=2161319; DOI=10.1007/978-3-642-74980-3_6;
RA Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R.,
RA Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A.,
RA Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
RT "Analysis of the protein-coding content of the sequence of human
RT cytomegalovirus strain AD169.";
RL Curr. Top. Microbiol. Immunol. 154:125-169(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9371656; DOI=10.1128/jvi.71.12.9833-9836.1997;
RA Dargan D.J., Jamieson F.E., Maclean J., Dolan A., Addison C., McGeoch D.J.;
RT "The published DNA sequence of human cytomegalovirus strain AD169 lacks 929
RT base pairs of DNA affecting genes UL42 and UL43.";
RL J. Virol. 71:9833-9836(1997).
RN [3]
RP GENOME REANNOTATION.
RX PubMed=12533697; DOI=10.1099/vir.0.18606-0;
RA Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA McGeoch D.J., Hayward G.S.;
RT "The human cytomegalovirus genome revisited: comparison with the chimpanzee
RT cytomegalovirus genome.";
RL J. Gen. Virol. 84:17-28(2003).
RN [4]
RP ERRATUM OF PUBMED:12533697.
RA Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA McGeoch D.J., Hayward G.S.;
RL J. Gen. Virol. 84:1053-1053(2003).
RN [5]
RP IDENTIFICATION, AND SUBCELLULAR LOCATION.
RX PubMed=15452216; DOI=10.1128/jvi.78.20.10960-10966.2004;
RA Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA Shenk T., Smith R.D., Nelson J.A.;
RT "Identification of proteins in human cytomegalovirus (HCMV) particles: the
RT HCMV proteome.";
RL J. Virol. 78:10960-10966(2004).
RN [6]
RP ERRATUM OF PUBMED:15452216.
RA Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA Shenk T., Smith R.D., Nelson J.A.;
RL J. Virol. 78:13395-13395(2004).
CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000269|PubMed:15452216};
CC Single-pass membrane protein {ECO:0000269|PubMed:15452216}.
CC -!- SIMILARITY: Belongs to the HHV-5 UL41A protein family. {ECO:0000305}.
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DR EMBL; X17403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Y13735; CAA74073.1; -; Genomic_DNA.
DR EMBL; BK000394; DAA00146.1; -; Genomic_DNA.
DR RefSeq; YP_081499.1; NC_006273.2.
DR DNASU; 3077475; -.
DR GeneID; 3077475; -.
DR KEGG; vg:3077475; -.
DR Proteomes; UP000008991; Genome.
DR Proteomes; UP000008992; Genome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR020141; Herpesvirus_UL41A.
DR Pfam; PF17591; UL41A; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Virion.
FT CHAIN 1..78
FT /note="Protein UL41A"
FT /id="PRO_0000115324"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 9
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 78 AA; 8953 MW; 41815D53118D7C4F CRC64;
MTLFCRTANS TAGYVDMNVC IGMIGVVCFV FGVFILIFCS TLKAFYVRQK TYHLLGTESD
DEETTVWEKR RMESDTDF