ID   UL43_HCMVM              Reviewed;         423 AA.
AC   Q6SW89; D2K3L0;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 51.
DE   RecName: Full=Tegument protein UL43;
GN   Name=UL43;
OS   Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=295027;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae US22 family. {ECO:0000305}.
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DR   EMBL; AY446894; AAR31607.1; -; Genomic_DNA.
DR   RefSeq; YP_081501.1; NC_006273.2.
DR   PRIDE; Q6SW89; -.
DR   DNASU; 3077512; -.
DR   GeneID; 3077512; -.
DR   KEGG; vg:3077512; -.
DR   Reactome; R-HSA-9609690; HCMV Early Events.
DR   Reactome; R-HSA-9610379; HCMV Late Events.
DR   Proteomes; UP000000938; Genome.
DR   GO; GO:0019033; C:viral tegument; TAS:Reactome.
DR   InterPro; IPR003360; US22-like.
DR   Pfam; PF02393; US22; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..423
FT                   /note="Tegument protein UL43"
FT                   /id="PRO_0000416718"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  47748 MW;  7D693A18C759408C CRC64;
     MEKTPAETTA VSAGNVPRDS IPCITNVSAD TRGRTRPSRP ATVPQRRPAR IGHFRRRSAS
     LSFLDWPDDS VTEGVRTTSA SVAASAARFD EIRRRRQSIN DEMKERTLED ALAVELVNET
     FRCSVTSDAR KDLQKLVRRV SGTVLRLSWP NGWFFTYCDL LRVGYFGHLN IKGLEKTFLC
     CDKFLLPVGT VSRCEAIGRP PLPVLIGEGG RVYVYSPVVE SLYLVSRSGF RGFVQEGLRN
     YAPLREELGY VRFETGGDVG REFMLARDLL ALWRLCMKRE GSIFSWRDGN EALTTVVLNG
     SQTYEDPAHG NWLKETCSLN VLQVFVVRAV PVESQQRLDI SILVNESGAV FGVHPDTRQA
     HFLARGLLGF FRVGFLRFCN NYCFARDCFT HPESVAPAYR ATGCPRELFC RRLRKKKGLF
     ARR