ID   ULAR_ECO57              Reviewed;         251 AA.
AC   P0A9W2; P39299;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=HTH-type transcriptional regulator UlaR {ECO:0000255|HAMAP-Rule:MF_01563};
GN   Name=ulaR {ECO:0000255|HAMAP-Rule:MF_01563};
GN   OrderedLocusNames=Z5800, ECs5167;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Represses ulaG and the ulaABCDEF operon. {ECO:0000255|HAMAP-
CC       Rule:MF_01563}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01563}.
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DR   EMBL; AE005174; AAG59387.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB38590.1; -; Genomic_DNA.
DR   PIR; G86115; G86115.
DR   PIR; G91274; G91274.
DR   RefSeq; NP_313194.1; NC_002695.1.
DR   RefSeq; WP_000133631.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0A9W2; -.
DR   SMR; P0A9W2; -.
DR   STRING; 155864.EDL933_5536; -.
DR   EnsemblBacteria; AAG59387; AAG59387; Z5800.
DR   EnsemblBacteria; BAB38590; BAB38590; ECs_5167.
DR   GeneID; 67414809; -.
DR   GeneID; 914012; -.
DR   KEGG; ece:Z5800; -.
DR   KEGG; ecs:ECs_5167; -.
DR   PATRIC; fig|386585.9.peg.5401; -.
DR   eggNOG; COG1349; Bacteria.
DR   HOGENOM; CLU_060699_3_2_6; -.
DR   OMA; RYDFFNF; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01563; HTH_type_UlaR; 1.
DR   InterPro; IPR014036; DeoR_C.
DR   InterPro; IPR001034; DeoR_HTH.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR   InterPro; IPR023711; Tscrpt_reg_HTH_UlaR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00455; DeoRC; 1.
DR   Pfam; PF08220; HTH_DeoR; 1.
DR   PRINTS; PR00037; HTHLACR.
DR   SMART; SM00420; HTH_DEOR; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00894; HTH_DEOR_1; 1.
DR   PROSITE; PS51000; HTH_DEOR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..251
FT                   /note="HTH-type transcriptional regulator UlaR"
FT                   /id="PRO_0000050278"
FT   DOMAIN          3..58
FT                   /note="HTH deoR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01563"
FT   DNA_BIND        20..39
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01563"
SQ   SEQUENCE   251 AA;  27602 MW;  797396226CFE01D6 CRC64;
     MTEAQRHQIL LEMLAQLGFV TVEKVVERLG ISPATARRDI NKLDESGKLK KVRNGAEAIT
     QQRPRWTPMN LHQAQNHDEK VRIAKAASQL VNPGESVVIN CGSTAFLLGR EMCGKPVQII
     TNYLPLANYL IDQEHDSVII MGGQYNKSQS ITLSPQGSEN SLYAGHWMFT SGKGLTAEGL
     YKTDMLTAMA EQKMLSVVGK LVVLVDSSKI GERAGMLFSR ADQIDMLITG KNANPEILQQ
     LEAQGVSILR V