ID   ULAR_ECOBW              Reviewed;         251 AA.
AC   C4ZR68;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=HTH-type transcriptional regulator UlaR {ECO:0000255|HAMAP-Rule:MF_01563};
GN   Name=ulaR {ECO:0000255|HAMAP-Rule:MF_01563}; OrderedLocusNames=BWG_3903;
OS   Escherichia coli (strain K12 / MC4100 / BW2952).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=595496;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MC4100 / BW2952;
RX   PubMed=19376874; DOI=10.1128/jb.00118-09;
RA   Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA   Wang L.;
RT   "Genomic sequencing reveals regulatory mutations and recombinational events
RT   in the widely used MC4100 lineage of Escherichia coli K-12.";
RL   J. Bacteriol. 191:4025-4029(2009).
CC   -!- FUNCTION: Represses ulaG and the ulaABCDEF operon. {ECO:0000255|HAMAP-
CC       Rule:MF_01563}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01563}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001396; ACR62926.1; -; Genomic_DNA.
DR   RefSeq; WP_000133631.1; NC_012759.1.
DR   AlphaFoldDB; C4ZR68; -.
DR   SMR; C4ZR68; -.
DR   GeneID; 67414809; -.
DR   KEGG; ebw:BWG_3903; -.
DR   HOGENOM; CLU_060699_3_2_6; -.
DR   OMA; RYDFFNF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01563; HTH_type_UlaR; 1.
DR   InterPro; IPR014036; DeoR_C.
DR   InterPro; IPR001034; DeoR_HTH.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR   InterPro; IPR023711; Tscrpt_reg_HTH_UlaR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00455; DeoRC; 1.
DR   Pfam; PF08220; HTH_DeoR; 1.
DR   PRINTS; PR00037; HTHLACR.
DR   SMART; SM00420; HTH_DEOR; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00894; HTH_DEOR_1; 1.
DR   PROSITE; PS51000; HTH_DEOR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..251
FT                   /note="HTH-type transcriptional regulator UlaR"
FT                   /id="PRO_1000215512"
FT   DOMAIN          3..58
FT                   /note="HTH deoR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01563"
FT   DNA_BIND        20..39
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01563"
SQ   SEQUENCE   251 AA;  27602 MW;  797396226CFE01D6 CRC64;
     MTEAQRHQIL LEMLAQLGFV TVEKVVERLG ISPATARRDI NKLDESGKLK KVRNGAEAIT
     QQRPRWTPMN LHQAQNHDEK VRIAKAASQL VNPGESVVIN CGSTAFLLGR EMCGKPVQII
     TNYLPLANYL IDQEHDSVII MGGQYNKSQS ITLSPQGSEN SLYAGHWMFT SGKGLTAEGL
     YKTDMLTAMA EQKMLSVVGK LVVLVDSSKI GERAGMLFSR ADQIDMLITG KNANPEILQQ
     LEAQGVSILR V