ULE4_CAEEL
ID ULE4_CAEEL Reviewed; 111 AA.
AC O62053;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=UPF0375 protein ule-4 {ECO:0000305};
DE Flags: Precursor;
GN Name=ule-4 {ECO:0000312|WormBase:C08F11.11};
GN ORFNames=C08F11.11 {ECO:0000312|WormBase:C08F11.11};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-58, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=12754521; DOI=10.1038/nbt829;
RA Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA Kasai K., Takahashi N., Isobe T.;
RT "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT identify N-linked glycoproteins.";
RL Nat. Biotechnol. 21:667-672(2003).
RN [3]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-58, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Bristol N2;
RX PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA Taoka M., Takahashi N., Isobe T.;
RT "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT elegans and suggests an atypical translocation mechanism for integral
RT membrane proteins.";
RL Mol. Cell. Proteomics 6:2100-2109(2007).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0375 family. {ECO:0000305}.
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DR EMBL; BX284604; CAB05678.1; -; Genomic_DNA.
DR PIR; T19094; T19094.
DR RefSeq; NP_502635.1; NM_070234.4.
DR AlphaFoldDB; O62053; -.
DR BioGRID; 43415; 1.
DR IntAct; O62053; 1.
DR STRING; 6239.C08F11.11.1; -.
DR iPTMnet; O62053; -.
DR EPD; O62053; -.
DR PaxDb; O62053; -.
DR PeptideAtlas; O62053; -.
DR EnsemblMetazoa; C08F11.11.1; C08F11.11.1; WBGene00007458.
DR EnsemblMetazoa; C08F11.11.2; C08F11.11.2; WBGene00007458.
DR GeneID; 178331; -.
DR KEGG; cel:CELE_C08F11.11; -.
DR UCSC; C08F11.11; c. elegans.
DR CTD; 178331; -.
DR WormBase; C08F11.11; CE17388; WBGene00007458; ule-4.
DR GeneTree; ENSGT00390000003521; -.
DR HOGENOM; CLU_2160659_0_0_1; -.
DR PhylomeDB; O62053; -.
DR PRO; PR:O62053; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00007458; Expressed in adult organism and 2 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR009981; DUF1505.
DR Pfam; PF07403; DUF1505; 1.
PE 1: Evidence at protein level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..111
FT /note="UPF0375 protein ule-4"
FT /evidence="ECO:0000305"
FT /id="PRO_0000248523"
FT CARBOHYD 23
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 58
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000269|PubMed:12754521,
FT ECO:0000269|PubMed:17761667"
SQ SEQUENCE 111 AA; 11832 MW; 346D25C8837BC424 CRC64;
MNSRLVLLLA VSVALVSAIA VGNRSSHLKK SKECSSDGHT ERCEYTGDLT VKTDSTCNHS
TYIMTKVTPP NESPSNGVAH CRTAPCNSED YADVDCLVAF GADNIAAIEK Q
