ULP1B_ARATH
ID ULP1B_ARATH Reviewed; 341 AA.
AC O65278; F4JHF6;
DT 10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Putative ubiquitin-like-specific protease 1B;
DE EC=3.4.22.-;
GN Name=ULP1B; OrderedLocusNames=At4g00690; ORFNames=F6N23.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP IDENTIFICATION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12482876; DOI=10.1074/jbc.m209694200;
RA Kurepa J., Walker J.M., Smalle J., Gosink M.M., Davis S.J., Durham T.L.,
RA Sung D.Y., Vierstra R.D.;
RT "The small ubiquitin-like modifier (SUMO) protein modification system in
RT Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by
RT stress.";
RL J. Biol. Chem. 278:6862-6872(2003).
RN [4]
RP IDENTIFICATION.
RX PubMed=16740136; DOI=10.1042/bj20060426;
RA Chosed R., Mukherjee S., Lois L.M., Orth K.;
RT "Evolution of a signalling system that incorporates both redundancy and
RT diversity: Arabidopsis SUMOylation.";
RL Biochem. J. 398:521-529(2006).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16920872; DOI=10.1104/pp.106.085415;
RA Colby T., Matthai A., Boeckelmann A., Stuible H.P.;
RT "SUMO-conjugating and SUMO-deconjugating enzymes from Arabidopsis.";
RL Plant Physiol. 142:318-332(2006).
CC -!- FUNCTION: Protease that catalyzes two essential functions in the SUMO
CC pathway: processing of full-length SUMOs to their mature forms and
CC deconjugation of SUMO from targeted proteins. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peptidase C48 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC13629.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB80878.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF058919; AAC13629.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161472; CAB80878.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE81919.2; -; Genomic_DNA.
DR PIR; T01233; T01233.
DR RefSeq; NP_001319834.1; NM_001340261.1.
DR AlphaFoldDB; O65278; -.
DR SMR; O65278; -.
DR STRING; 3702.AT4G00690.1; -.
DR MEROPS; C48.A01; -.
DR PaxDb; O65278; -.
DR PRIDE; O65278; -.
DR ProteomicsDB; 245307; -.
DR EnsemblPlants; AT4G00690.1; AT4G00690.1; AT4G00690.
DR GeneID; 828036; -.
DR Gramene; AT4G00690.1; AT4G00690.1; AT4G00690.
DR KEGG; ath:AT4G00690; -.
DR Araport; AT4G00690; -.
DR eggNOG; KOG0778; Eukaryota.
DR HOGENOM; CLU_024324_4_1_1; -.
DR InParanoid; O65278; -.
DR OMA; IDISSWD; -.
DR OrthoDB; 1480705at2759; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O65278; baseline and differential.
DR Genevisible; O65278; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016929; F:deSUMOylase activity; IBA:GO_Central.
DR GO; GO:0016926; P:protein desumoylation; IBA:GO_Central.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR003653; Peptidase_C48_C.
DR Pfam; PF02902; Peptidase_C48; 1.
DR SUPFAM; SSF54001; SSF54001; 1.
DR PROSITE; PS50600; ULP_PROTEASE; 1.
PE 5: Uncertain;
KW Hydrolase; Protease; Reference proteome; Thiol protease;
KW Ubl conjugation pathway.
FT CHAIN 1..341
FT /note="Putative ubiquitin-like-specific protease 1B"
FT /id="PRO_0000395969"
FT ACT_SITE 231
FT /evidence="ECO:0000250"
FT ACT_SITE 248
FT /evidence="ECO:0000250"
FT ACT_SITE 300
FT /evidence="ECO:0000250"
SQ SEQUENCE 341 AA; 39695 MW; B58DCAA6E5269CE2 CRC64;
MALVPKIRNR TISDKPVSSS CTRTSSFRQR LLASCKRFLR FKLLVRASSV SLKKKAARCS
QSQQVVKHND DRIEEHSSSN RGFKDGNNFL VSSTETKKLV AFCGEPFQPL NEEEVALVNS
ALSKRNRKKI LVSHKNSNID ISGETLQCLR PNQWLNDDVT NLYLELLKER QTRDPQKYFK
CHFFNTFFYV KLVSGSGYNY KAVSRWTTKR KLGYDLIDCD IIFVPIHIDI HWTLGVINNR
ERKFVYLDSL FTGVGHTILN AMAKYLVDEV KQKSQKNIDV SSWGMEYVEE RPQQQNGYDC
GMFMLKYIDF YSRGLSLQFS QKDMPYFRLR TAKEILRLRA D
