UMP1_SCHPO
ID UMP1_SCHPO Reviewed; 129 AA.
AC O74416;
DT 21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Probable proteasome maturation factor ump1;
GN Name=ump1; ORFNames=SPCC14G10.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Short-lived chaperone present in the precursor form of the
CC 20S proteasome and absent in the mature complex. Required for the
CC correct assembly and enzymatic activation of the proteasome (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the POMP/UMP1 family. {ECO:0000305}.
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DR EMBL; CU329672; CAA20656.1; -; Genomic_DNA.
DR PIR; T41014; T41014.
DR RefSeq; NP_587944.1; NM_001022935.2.
DR AlphaFoldDB; O74416; -.
DR SMR; O74416; -.
DR BioGRID; 275694; 4.
DR STRING; 4896.SPCC14G10.03c.1; -.
DR MaxQB; O74416; -.
DR PaxDb; O74416; -.
DR EnsemblFungi; SPCC14G10.03c.1; SPCC14G10.03c.1:pep; SPCC14G10.03c.
DR GeneID; 2539122; -.
DR KEGG; spo:SPCC14G10.03c; -.
DR PomBase; SPCC14G10.03c; ump1.
DR VEuPathDB; FungiDB:SPCC14G10.03c; -.
DR eggNOG; KOG3061; Eukaryota.
DR HOGENOM; CLU_2005237_0_0_1; -.
DR InParanoid; O74416; -.
DR OMA; IYGLHEP; -.
DR PhylomeDB; O74416; -.
DR PRO; PR:O74416; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0043248; P:proteasome assembly; ISO:PomBase.
DR InterPro; IPR008012; Ump1.
DR PANTHER; PTHR12828; PTHR12828; 1.
DR Pfam; PF05348; UMP1; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..129
FT /note="Probable proteasome maturation factor ump1"
FT /id="PRO_0000065719"
SQ SEQUENCE 129 AA; 14661 MW; 36CAE66B313BE4C1 CRC64;
MKIVPDVEPA AEVSGNFKVS VLEPSIPAVH RVENKHPLES RLKNWEAQQQ QIRLDSMRRI
YGLHEPVRRE MEQKLASQSS RPLALGGSAN FHLDILANRE AVLDETDIYA APIPLEMTYQ
NEMAIRYGL