ID   UN93A_MOUSE             Reviewed;         458 AA.
AC   Q710D3;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Protein unc-93 homolog A;
DE            Short=Unc-93A;
GN   Name=Unc93a;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Embryo;
RA   Kollewe A.;
RT   "Cloning and characterization of mammalian homologs of unc-93 from
RT   Caenorhabditis elegans, a protein relevant for muscle contraction.";
RL   Thesis (2001), University of Hannover, Germany.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the unc-93 family. {ECO:0000305}.
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DR   EMBL; AJ422143; CAD19523.1; -; mRNA.
DR   CCDS; CCDS28402.1; -.
DR   RefSeq; NP_954860.1; NM_199252.2.
DR   RefSeq; XP_011244517.1; XM_011246215.2.
DR   RefSeq; XP_011244518.1; XM_011246216.1.
DR   RefSeq; XP_011244519.1; XM_011246217.2.
DR   RefSeq; XP_011244520.1; XM_011246218.2.
DR   AlphaFoldDB; Q710D3; -.
DR   SMR; Q710D3; -.
DR   STRING; 10090.ENSMUSP00000082032; -.
DR   GlyGen; Q710D3; 1 site.
DR   PaxDb; Q710D3; -.
DR   PRIDE; Q710D3; -.
DR   DNASU; 381058; -.
DR   Ensembl; ENSMUST00000084966; ENSMUSP00000082032; ENSMUSG00000067049.
DR   Ensembl; ENSMUST00000232960; ENSMUSP00000156970; ENSMUSG00000067049.
DR   Ensembl; ENSMUST00000233405; ENSMUSP00000156756; ENSMUSG00000067049.
DR   GeneID; 381058; -.
DR   KEGG; mmu:381058; -.
DR   UCSC; uc008amc.1; mouse.
DR   CTD; 54346; -.
DR   MGI; MGI:1933250; Unc93a.
DR   VEuPathDB; HostDB:ENSMUSG00000067049; -.
DR   eggNOG; KOG3097; Eukaryota.
DR   GeneTree; ENSGT00530000063359; -.
DR   HOGENOM; CLU_025356_1_1_1; -.
DR   InParanoid; Q710D3; -.
DR   OMA; FLCLEYK; -.
DR   OrthoDB; 1145833at2759; -.
DR   PhylomeDB; Q710D3; -.
DR   TreeFam; TF314905; -.
DR   BioGRID-ORCS; 381058; 2 hits in 40 CRISPR screens.
DR   PRO; PR:Q710D3; -.
DR   Proteomes; UP000000589; Chromosome 17.
DR   RNAct; Q710D3; protein.
DR   Bgee; ENSMUSG00000067049; Expressed in testis and 16 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISO:MGI.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR010291; Ion_channel_UNC-93.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF05978; UNC-93; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..458
FT                   /note="Protein unc-93 homolog A"
FT                   /id="PRO_0000190037"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        190
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   458 AA;  50370 MW;  AB405CCA4E1BA9A8 CRC64;
     MERSLKNVLV VSCGFLLLFT AYGGLQNLQS SLYSEQGLGV ATLSTLYASV LLSSMFLPPI
     LIKKCGCKWT IVGSMCCYVV FSLGNFHANW YTLIPTSILL GLGAAPLWSA QGTYLTTMGN
     LQAEKVGKLG KDVVNQYFGI FFLVFQSSGV WGNLISSLVF GKMSMQEAIP EEQLMSCGAK
     DCLMGPAATN STHHPSQQLI YTLLGIYTGC GVLAILLVAV FLESLEDKLE NEGERRPRPP
     PLWSTLLSTF MLFRDKRLCL LMFLPLYSGF QQEFLSGEYT KSYVTCALGI HFVGYVMICF
     SAMTALCSLL YGKISKYTGR AALYALGAAI HFSCIVVFLL WHPNTNQLPV FFVLSGLWGM
     SDAVWQTQNN ALFGVLFEEN KEPAFANYRL GEAIGFVIAF GYSSFLCVST KLYILLGVLS
     LAMVGYGTVE YLEVKAASKV LGAEKKNQAE EEEMKTKI