ID   UNAP_MIMIV              Reviewed;         255 AA.
AC   Q5UNV4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   07-OCT-2020, entry version 53.
DE   RecName: Full=Probable UDP-N-acetylglucosamine pyrophosphorylase;
DE            EC=2.7.7.23;
DE   AltName: Full=N-acetylglucosamine-1-phosphate uridyltransferase;
GN   OrderedLocusNames=MIMI_R689;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP =
CC         diphosphate + UDP-N-acetyl-alpha-D-glucosamine; Xref=Rhea:RHEA:13509,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:46398,
CC         ChEBI:CHEBI:57705, ChEBI:CHEBI:57776; EC=2.7.7.23;
CC   -!- PATHWAY: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-
CC       glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-
CC       acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
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DR   EMBL; AY653733; AAV50950.1; -; Genomic_DNA.
DR   RefSeq; YP_003987216.1; NC_014649.1.
DR   SMR; Q5UNV4; -.
DR   GeneID; 9925340; -.
DR   KEGG; vg:9925340; -.
DR   UniPathway; UPA00113; UER00533.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0003977; F:UDP-N-acetylglucosamine diphosphorylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..255
FT                   /note="Probable UDP-N-acetylglucosamine pyrophosphorylase"
FT                   /id="PRO_0000071172"
SQ   SEQUENCE   255 AA;  29062 MW;  CA8BA16E62FE7D26 CRC64;
     MGKTNVSHKL YITLLAGGMG KRMQSNLPKV LHKVNGETMI VRLMKQVIKL NPDKILVVVG
     KFYSEISSEI KQHINDNRIE FVVQKEPLGT GDAVKCTLPL LINDNIDNII LNGDVPMIQH
     STIKNIYNYY LETKSKLLIT SIHLSNPTGC GRIILDENFG FSEIIEEKDC TEDQKKLTLV
     NCGIYVCNSK ILKQSIPQIS NNNSQKEYYL TDLVKIYNNE PSNNINLFIL PRNKEIEIYN
     INTKEQLEYI ESVSK