UNC50_DICDI
ID UNC50_DICDI Reviewed; 261 AA.
AC Q54DD7;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Protein unc-50 homolog;
GN ORFNames=DDB_G0292320;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the unc-50 family. {ECO:0000305}.
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DR EMBL; AAFI02000189; EAL61284.1; -; Genomic_DNA.
DR RefSeq; XP_629704.1; XM_629702.1.
DR AlphaFoldDB; Q54DD7; -.
DR STRING; 44689.DDB0266485; -.
DR PaxDb; Q54DD7; -.
DR EnsemblProtists; EAL61284; EAL61284; DDB_G0292320.
DR GeneID; 8628618; -.
DR KEGG; ddi:DDB_G0292320; -.
DR dictyBase; DDB_G0292320; -.
DR eggNOG; KOG3012; Eukaryota.
DR HOGENOM; CLU_066239_1_0_1; -.
DR InParanoid; Q54DD7; -.
DR OMA; ISTLMWV; -.
DR PhylomeDB; Q54DD7; -.
DR PRO; PR:Q54DD7; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR InterPro; IPR007881; UNC-50.
DR PANTHER; PTHR12841; PTHR12841; 1.
DR Pfam; PF05216; UNC-50; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..261
FT /note="Protein unc-50 homolog"
FT /id="PRO_0000327856"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 261 AA; 30772 MW; 1745A17B5A23CFC1 CRC64;
MLPISYTNLN SSRITRDGTA SSASRYRRLI PEYFRRIFHY PQMDIEYTFW IMFYLCFNPS
RVYRVTSWHK QTKNQWARDD PAFAVILVFF MAIASMSYAI TFHFLSFLNV IKVMFWAVFV
DFITVGLLIA TIGWWVTNKF LRVSVHNHSV DQSVEWLYAF DIHCNSFFPL FIILYVVQFF
LLPILLSNSL FAAILSNTLY IIGFSYYYYV TFLGYNALPF LQHTVVFLYP IGILFALYIV
SVVMGKNLTV SIINFYFGFQ L
