UNTX_CENLI
ID UNTX_CENLI Reviewed; 29 AA.
AC P0DL69;
DT 05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2017, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=Orphan peptide CllNtx {ECO:0000303|PubMed:27889600};
OS Centruroides limpidus (Mexican scorpion).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC Scorpiones; Buthida; Buthoidea; Buthidae; Centruroides.
OX NCBI_TaxID=6876;
RN [1]
RP PROTEIN SEQUENCE, AND SUBCELLULAR LOCATION.
RC TISSUE=Venom;
RX PubMed=27889600; DOI=10.1016/j.toxicon.2016.11.256;
RA Cid Uribe J.I., Jimenez Vargas J.M., Ferreira Batista C.V.,
RA Zamudio Zuniga F., Possani L.D.;
RT "Comparative proteomic analysis of female and male venoms from the Mexican
RT scorpion Centruroides limpidus: novel components found.";
RL Toxicon 125:91-98(2017).
CC -!- FUNCTION: May act as a toxin. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27889600}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:27889600}.
CC -!- PTM: Contains 3 disulfide bonds. {ECO:0000305}.
CC -!- MISCELLANEOUS: This toxin is only found in male specimens.
CC {ECO:0000269|PubMed:27889600}.
CC -!- MISCELLANEOUS: Does not show toxicity when intracranially injected into
CC mice or when injected into insects (A.domestica). Does not show effect
CC when injected into female scorpion. Does not show antimicrobial
CC activity. Does not show activity on Kv10.1/KCNH1/EAG1 and Shaker
CC channels. {ECO:0000269|PubMed:27889600}.
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DR AlphaFoldDB; P0DL69; -.
DR SMR; P0DL69; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT PEPTIDE 1..29
FT /note="Orphan peptide CllNtx"
FT /evidence="ECO:0000269|PubMed:27889600"
FT /id="PRO_0000440866"
SQ SEQUENCE 29 AA; 3393 MW; 64149B92A916C679 CRC64;
KYCYNDDDCK SECMVVKYCQ QGTCYCKGN