CA216_MOUSE
ID CA216_MOUSE Reviewed; 230 AA.
AC Q8BP99; A2A7K4;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 2.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=UPF0500 protein C1orf216 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SIMILARITY: Belongs to the UPF0500 family. {ECO:0000305}.
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DR EMBL; AK077438; BAC36801.1; -; mRNA.
DR EMBL; AL606935; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS18656.1; -.
DR RefSeq; NP_001013777.2; NM_001013755.3.
DR RefSeq; NP_001139422.1; NM_001145950.1.
DR AlphaFoldDB; Q8BP99; -.
DR SMR; Q8BP99; -.
DR BioGRID; 231015; 1.
DR iPTMnet; Q8BP99; -.
DR PhosphoSitePlus; Q8BP99; -.
DR MaxQB; Q8BP99; -.
DR PaxDb; Q8BP99; -.
DR PeptideAtlas; Q8BP99; -.
DR PRIDE; Q8BP99; -.
DR Antibodypedia; 31583; 85 antibodies from 17 providers.
DR Ensembl; ENSMUST00000097886; ENSMUSP00000095496; ENSMUSG00000073755.
DR Ensembl; ENSMUST00000164362; ENSMUSP00000128538; ENSMUSG00000073755.
DR GeneID; 230757; -.
DR KEGG; mmu:230757; -.
DR UCSC; uc008utp.2; mouse.
DR MGI; MGI:3609248; 5730409E04Rik.
DR VEuPathDB; HostDB:ENSMUSG00000073755; -.
DR eggNOG; ENOG502S1PX; Eukaryota.
DR GeneTree; ENSGT00390000001867; -.
DR HOGENOM; CLU_1156086_0_0_1; -.
DR InParanoid; Q8BP99; -.
DR OMA; GMPGKVE; -.
DR OrthoDB; 1593675at2759; -.
DR PhylomeDB; Q8BP99; -.
DR TreeFam; TF335932; -.
DR BioGRID-ORCS; 230757; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q8BP99; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q8BP99; protein.
DR Bgee; ENSMUSG00000073755; Expressed in dentate gyrus of hippocampal formation granule cell and 178 other tissues.
DR Genevisible; Q8BP99; MM.
DR InterPro; IPR027812; DUF4653.
DR PANTHER; PTHR35673; PTHR35673; 1.
DR Pfam; PF15546; DUF4653; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..230
FT /note="UPF0500 protein C1orf216 homolog"
FT /id="PRO_0000309179"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 215
FT /note="R -> H (in Ref. 1; BAC36801)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 230 AA; 25232 MW; 0E3E5F46FE7BE904 CRC64;
MFAAIQPGLA EGAQYPGSLP PGVCQPDLQP DNNSNFVESA KDANKNWHGV PGKVDPILIR
SSSESPSDNQ VFQATRLPEA GVRSPPEGAE IPGAEPEKLS GASSVCSPLE DIGYASSSLS
IDSFSSSPEP VCDTPRGPSP LDPLLPSVAQ AVQQLQAQER YKEQEKEKHH AHLVMYRRLA
LLQWIRALQH QLVDQQARLQ ESFDTILDNR KELIRCLQQR EAPCRHQDQG
