ID   UP3_RAT                 Reviewed;         101 AA.
AC   P83121;
DT   27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Urinary protein 3;
DE            Short=UP-3;
DE            Short=rUP-3;
DE   Flags: Precursor;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Sprague-Dawley;
RA   Soares M.B.;
RL   Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 27-40.
RC   STRAIN=Lewis, Sprague-Dawley, and Wistar Kyoto; TISSUE=Urine;
RX   PubMed=11565799;
RX   DOI=10.1002/1522-2683(200108)22:14<3043::aid-elps3043>3.0.co;2-m;
RA   Wait R., Gianazza E., Eberini I., Sironi L., Dunn M.J., Gemeiner M.,
RA   Miller I.;
RT   "Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein
RT   identifications and interstrain comparison.";
RL   Electrophoresis 22:3043-3052(2001).
RN   [3]
RP   IDENTIFICATION.
RC   TISSUE=Urine;
RX   PubMed=11840564;
RX   DOI=10.1002/1615-9861(200202)2:2<187::aid-prot187>3.0.co;2-a;
RA   Southan C., Cutler P., Birrell H., Connell J., Fantom K.G.M., Sims M.,
RA   Shaikh N., Schneider K.;
RT   "The characterisation of novel secreted Ly-6 proteins from rat urine by the
RT   combined use of two-dimensional gel electrophoresis, microbore high
RT   performance liquid chromatography and expressed sequence tag data.";
RL   Proteomics 2:187-196(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   EMBL; AA818561; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P83121; -.
DR   SMR; P83121; -.
DR   UCSC; RGD:1592962; rat.
DR   RGD; 1592962; LOC680367.
DR   InParanoid; P83121; -.
DR   PhylomeDB; P83121; -.
DR   TreeFam; TF337781; -.
DR   PRO; PR:P83121; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Disulfide bond; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..101
FT                   /note="Urinary protein 3"
FT                   /id="PRO_0000036171"
FT   DOMAIN          22..99
FT                   /note="UPAR/Ly6"
FT                   /evidence="ECO:0000305"
FT   DISULFID        24..51
FT                   /evidence="ECO:0000255"
FT   DISULFID        27..36
FT                   /evidence="ECO:0000255"
FT   DISULFID        43..70
FT                   /evidence="ECO:0000255"
FT   DISULFID        73..89
FT                   /evidence="ECO:0000255"
FT   DISULFID        90..96
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   101 AA;  11100 MW;  5E0B564E0899134C CRC64;
     MGKHILLLPL GLSLLMSSLL ALQCFRCISF DSTGFCYVGR HICQTYPDEI CAWVVVTTRD
     GKFVYGNQSC AECNATTVEH GSLIVSTNCC SATPFCNMVH R