ID   UPE22_UPEIN             Reviewed;          19 AA.
AC   P82028;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Uperin-2.2;
OS   Uperoleia inundata (Floodplain toadlet).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Myobatrachoidea; Myobatrachidae;
OC   Myobatrachinae; Uperoleia.
OX   NCBI_TaxID=104953;
RN   [1]
RP   PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RC   TISSUE=Skin secretion;
RA   Bradford A.M., Raftery M.J., Bowie J.H., Tyler M.J., Wallace J.C.,
RA   Adams G.W., Severini C.;
RT   "Novel uperin peptides from the dorsal glands of the australian floodplain
RT   toadlet Uperoleia inundata.";
RL   Aust. J. Chem. 49:475-484(1996).
CC   -!- FUNCTION: Shows a weak antibacterial activity against B.cereus, E.coli,
CC       L.mesenteriodes, L.innocua, M.luteus, P.haemolytica, S.aureus and
CC       S.uberis.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin dorsal glands.
CC   -!- MASS SPECTROMETRY: Mass=1926; Method=FAB; Evidence={ECO:0000269|Ref.1};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P82028; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR013157; Aurein_antimicrobial_peptide.
DR   Pfam; PF08256; Antimicrobial20; 1.
PE   1: Evidence at protein level;
KW   Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..19
FT                   /note="Uperin-2.2"
FT                   /id="PRO_0000043847"
SQ   SEQUENCE   19 AA;  1927 MW;  3283EF077BA35B70 CRC64;
     GFVDLAKKVV GGIRNALGI