ID   UPE36_UPEMJ             Reviewed;          17 AA.
AC   P82043;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   18-JAN-2017, sequence version 2.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Uperin-3.6;
OS   Uperoleia mjobergii (Mjoberg's toadlet) (Pseudophryne mjobergii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Myobatrachoidea; Myobatrachidae;
OC   Myobatrachinae; Uperoleia.
OX   NCBI_TaxID=104954;
RN   [1]
RP   PROTEIN SEQUENCE, AMIDATION AT PHE-17, AND MASS SPECTROMETRY.
RC   TISSUE=Skin secretion;
RA   Bradford A.M., Bowie J.H., Tyler M.J., Wallace J.C.;
RT   "New antibiotic uperin peptides from the dorsal glands of the australian
RT   toadlet Uperoleia mjobergii.";
RL   Aust. J. Chem. 49:1325-1331(1996).
CC   -!- FUNCTION: Shows antibacterial activity against B.cereus, L.lactis,
CC       L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin dorsal glands.
CC   -!- MASS SPECTROMETRY: Mass=1826; Method=FAB; Evidence={ECO:0000269|Ref.1};
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DR   AlphaFoldDB; P82043; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..17
FT                   /note="Uperin-3.6"
FT                   /id="PRO_0000043859"
FT   MOD_RES         17
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   17 AA;  1828 MW;  66ED8BB46263CA3D CRC64;
     GVIDAAKKVV NVLKNLF