CAAT9_ARATH
ID CAAT9_ARATH Reviewed; 569 AA.
AC Q9C5D6; Q9LNF0;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Cationic amino acid transporter 9, chloroplastic;
DE Flags: Precursor;
GN Name=CAT9; OrderedLocusNames=At1g05940; ORFNames=T21E18.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=15377779; DOI=10.1104/pp.104.045278;
RA Su Y.-H., Frommer W.B., Ludewig U.;
RT "Molecular and functional characterization of a family of amino acid
RT transporters from Arabidopsis.";
RL Plant Physiol. 136:3104-3113(2004).
CC -!- FUNCTION: Permease involved in the transport of the cationic amino
CC acids. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane; Multi-pass
CC membrane protein.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, flowers, and leaves.
CC {ECO:0000269|PubMed:15377779}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF80119.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC024174; AAF80119.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27921.1; -; Genomic_DNA.
DR EMBL; AF360321; AAK26031.1; -; mRNA.
DR EMBL; AY113890; AAM44938.1; -; mRNA.
DR PIR; E86194; E86194.
DR RefSeq; NP_563754.1; NM_100475.4.
DR AlphaFoldDB; Q9C5D6; -.
DR SMR; Q9C5D6; -.
DR BioGRID; 22346; 12.
DR IntAct; Q9C5D6; 9.
DR STRING; 3702.AT1G05940.1; -.
DR iPTMnet; Q9C5D6; -.
DR SwissPalm; Q9C5D6; -.
DR PaxDb; Q9C5D6; -.
DR PRIDE; Q9C5D6; -.
DR ProteomicsDB; 240458; -.
DR EnsemblPlants; AT1G05940.1; AT1G05940.1; AT1G05940.
DR GeneID; 837104; -.
DR Gramene; AT1G05940.1; AT1G05940.1; AT1G05940.
DR KEGG; ath:AT1G05940; -.
DR Araport; AT1G05940; -.
DR TAIR; locus:2198861; AT1G05940.
DR eggNOG; KOG1286; Eukaryota.
DR HOGENOM; CLU_007946_15_10_1; -.
DR InParanoid; Q9C5D6; -.
DR OrthoDB; 439017at2759; -.
DR PhylomeDB; Q9C5D6; -.
DR PRO; PR:Q9C5D6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C5D6; baseline and differential.
DR Genevisible; Q9C5D6; AT.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF13906; AA_permease_C; 1.
PE 2: Evidence at transcript level;
KW Amino-acid transport; Chloroplast; Membrane; Plastid; Reference proteome;
KW Transit peptide; Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..41
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 42..569
FT /note="Cationic amino acid transporter 9, chloroplastic"
FT /id="PRO_0000415785"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 502..522
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 528..548
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 569 AA; 60176 MW; 6CA2175C63329091 CRC64;
MGGHEGFSNQ RLSSATWFSH FRASALRSKS LPPPSSQTAV RSTSGDSLVR RLGLFDLILL
GVGASIGAGV FVVTGTVARD AGPGVTISFL LAGASCVLNA LCYAELSSRF PAVVGGAYMY
SYSAFNEITA FLVFVQLMLD YHIGAASISR SLASYAVALL ELFPALKGSI PLWMGSGKEL
LGGLLSLNIL APILLALLTL VLCQGVRESS AVNSVMTATK VVIVLVVICA GAFEIDVANW
SPFAPNGFKA VLTGATVVFF SYVGFDAVAN SAEESKNPQR DLPIGIMGSL LVCISLYIGV
CLVLTGMVPF SLLSEDAPLA EAFSSKGMKF VSILISIGAV AGLTTTLLVG LYVQSRLYLG
LGRDGLLPSI FSRIHPTLHT PLHSQIWCGI VAGVLAGIFN VHSLSHILSV GTLTGYSVVA
ACVVALRLND KKDRESSNRW TSSWQEGVIC LVIIACSGFG AGVFYRFSAS VIFILLSVGV
AVVASAVLHY RQAYALPLGS GFSCPGVPIV PSVCIFFNIF LFAQLHYEAW IRFVVVSVLA
TAVYALYGQY HADPSMLDYQ RAPETESDA
