ID   UPS2_SCHPO              Reviewed;         184 AA.
AC   O59707;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=UPS-like protein C36.10;
GN   ORFNames=SPBC36.10;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for mitochondrial morphology. May control
CC       phospholipid metabolism in the mitochondrial intermembrane space (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC       Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Intermembrane side {ECO:0000250}. Mitochondrion
CC       intermembrane space {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the slowmo family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA19058.1; -; Genomic_DNA.
DR   PIR; T40305; T40305.
DR   RefSeq; NP_595338.1; NM_001021246.2.
DR   AlphaFoldDB; O59707; -.
DR   SMR; O59707; -.
DR   BioGRID; 277438; 24.
DR   STRING; 4896.SPBC36.10.1; -.
DR   MaxQB; O59707; -.
DR   PaxDb; O59707; -.
DR   EnsemblFungi; SPBC36.10.1; SPBC36.10.1:pep; SPBC36.10.
DR   GeneID; 2540922; -.
DR   KEGG; spo:SPBC36.10; -.
DR   PomBase; SPBC36.10; -.
DR   VEuPathDB; FungiDB:SPBC36.10; -.
DR   eggNOG; KOG3336; Eukaryota.
DR   HOGENOM; CLU_067902_1_1_1; -.
DR   InParanoid; O59707; -.
DR   OMA; AMSRRVF; -.
DR   PhylomeDB; O59707; -.
DR   Reactome; R-SPO-6803204; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release.
DR   PRO; PR:O59707; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; ISO:PomBase.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; ISO:PomBase.
DR   GO; GO:1990050; F:phosphatidic acid transfer activity; ISO:PomBase.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IC:PomBase.
DR   GO; GO:0045332; P:phospholipid translocation; ISO:PomBase.
DR   GO; GO:0015914; P:phospholipid transport; IBA:GO_Central.
DR   InterPro; IPR006797; PRELI/MSF1_dom.
DR   InterPro; IPR037365; Slowmo/Ups.
DR   PANTHER; PTHR11158; PTHR11158; 1.
DR   Pfam; PF04707; PRELI; 1.
DR   PROSITE; PS50904; PRELI_MSF1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome.
FT   CHAIN           1..184
FT                   /note="UPS-like protein C36.10"
FT                   /id="PRO_0000346780"
FT   DOMAIN          1..172
FT                   /note="PRELI/MSF1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00158"
SQ   SEQUENCE   184 AA;  21088 MW;  9654025A9265FA12 CRC64;
     MKIFESCHLF QYPFEQVSAA HWQKYPNEHA THVIAVDTLD RKVLDNGVLY TERLITCHQA
     LPRWILKLID GAQDCYIRET SYVDLKARTL TLLTSNLTFS DRLRVDETVT YSPHPELEAT
     VFQQEARIEA LACMKRLSNL IEQWSVDGFG KKASRGKEGF ESVLEKINMS VFQTRPFGSS
     EATA