ID   UQCC3_DANRE             Reviewed;          78 AA.
AC   B3DFP2;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 2.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Ubiquinol-cytochrome-c reductase complex assembly factor 3 {ECO:0000250|UniProtKB:Q6UW78};
GN   Name=uqcc3 {ECO:0000250|UniProtKB:Q6UW78}; ORFNames=si:dkey-88p24.9;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the assembly of the ubiquinol-cytochrome c
CC       reductase complex (mitochondrial respiratory chain complex III or
CC       cytochrome b-c1 complex), mediating cytochrome b recruitment and
CC       probably stabilization within the complex. Thereby, plays an important
CC       role in ATP production by mitochondria. Cardiolipin-binding protein, it
CC       may also control the cardiolipin composition of mitochondria membranes
CC       and their morphology. {ECO:0000250|UniProtKB:Q6UW78}.
CC   -!- SUBUNIT: Associates with the ubiquinol-cytochrome c reductase complex
CC       (mitochondrial respiratory chain complex III or cytochrome b-c1
CC       complex). {ECO:0000250|UniProtKB:Q6UW78}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q6UW78}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q6UW78}.
CC   -!- SIMILARITY: Belongs to the UQCC3 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI62114.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAI62114.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC162114; AAI62114.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001189365.1; NM_001202436.2.
DR   AlphaFoldDB; B3DFP2; -.
DR   SMR; B3DFP2; -.
DR   PeptideAtlas; B3DFP2; -.
DR   Ensembl; ENSDART00000132352; ENSDARP00000114572; ENSDARG00000093382.
DR   GeneID; 558925; -.
DR   KEGG; dre:558925; -.
DR   CTD; 790955; -.
DR   ZFIN; ZDB-GENE-030131-8451; uqcc3.
DR   GeneTree; ENSGT01050000246190; -.
DR   HOGENOM; CLU_184624_0_0_1; -.
DR   InParanoid; B3DFP2; -.
DR   OMA; VAWRKDW; -.
DR   OrthoDB; 1568049at2759; -.
DR   PhylomeDB; B3DFP2; -.
DR   PRO; PR:B3DFP2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000093382; Expressed in mature ovarian follicle and 27 other tissues.
DR   ExpressionAtlas; B3DFP2; baseline and differential.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:1901612; F:cardiolipin binding; ISS:UniProtKB.
DR   GO; GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0042407; P:cristae formation; ISS:UniProtKB.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; ISS:UniProtKB.
DR   GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; ISS:UniProtKB.
DR   InterPro; IPR027896; UQCC3.
DR   PANTHER; PTHR36465; PTHR36465; 1.
DR   Pfam; PF15141; UQCC3; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..78
FT                   /note="Ubiquinol-cytochrome-c reductase complex assembly
FT                   factor 3"
FT                   /id="PRO_0000360985"
FT   TOPO_DOM        1..5
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000250|UniProtKB:Q6UW78"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        27..78
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250|UniProtKB:Q6UW78"
SQ   SEQUENCE   78 AA;  8649 MW;  0527187B83ED88F7 CRC64;
     MSGMRILTGS VALGGLTYAI WIIFSPGEER KKEILKSLPE ANPVRMEETR KRNAIMLQVL
     KDAAETNDNI ARGFGSQK