ID   URE23_PSEU2             Reviewed;         231 AA.
AC   Q4ZUD1;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Urease subunit gamma/beta {ECO:0000255|HAMAP-Rule:MF_01955};
DE            EC=3.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01955};
DE   AltName: Full=Urea amidohydrolase subunit gamma/beta {ECO:0000255|HAMAP-Rule:MF_01955};
GN   Name=ureAB {ECO:0000255|HAMAP-Rule:MF_01955}; OrderedLocusNames=Psyr_2198;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01955};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_01955}.
CC   -!- SUBUNIT: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta)
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_01955}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01955}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the urease gamma
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_01955}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the urease beta
CC       subunit family. {ECO:0000255|HAMAP-Rule:MF_01955}.
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DR   EMBL; CP000075; AAY37241.1; -; Genomic_DNA.
DR   RefSeq; WP_011267498.1; NC_007005.1.
DR   RefSeq; YP_235279.1; NC_007005.1.
DR   AlphaFoldDB; Q4ZUD1; -.
DR   SMR; Q4ZUD1; -.
DR   STRING; 205918.Psyr_2198; -.
DR   EnsemblBacteria; AAY37241; AAY37241; Psyr_2198.
DR   KEGG; psb:Psyr_2198; -.
DR   PATRIC; fig|205918.7.peg.2249; -.
DR   eggNOG; COG0831; Bacteria.
DR   eggNOG; COG0832; Bacteria.
DR   HOGENOM; CLU_000980_3_0_6; -.
DR   OMA; VECVFPD; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0035550; C:urease complex; IEA:InterPro.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   HAMAP; MF_01955; Urease_beta_gamma; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR008223; Urease_gamma-beta_su.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001225; Urease_gammabeta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase.
FT   CHAIN           1..231
FT                   /note="Urease subunit gamma/beta"
FT                   /id="PRO_0000234197"
FT   REGION          1..101
FT                   /note="Urease gamma"
FT   REGION          102..231
FT                   /note="Urease beta"
SQ   SEQUENCE   231 AA;  25007 MW;  C86F180D6166FA7A CRC64;
     MLLTPTELER LTLYTAAELS RKRRSKGLRL NFPEASALIA DEILEGAREG RSVAELIGFG
     STILNTDDVM PGVADLLPVL QVEGTFPDGT KLVTVHQPIR PGQLPLAVMP TPGEILAPDG
     DIHLNGDRPT ATLRAINTGD RPVQIGSHYH FFEVNKALDF PRERAFGMHL DIPAGTAVRF
     EPGELREVQL VQFGGTGDIH GFSGLTNGNL HDPACKLAAL ERARAQFFKG A