ID   URE2_HALMA              Reviewed;         138 AA.
AC   Q75ZQ6; Q5V6L8;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Urease subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
DE            EC=3.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01954};
DE   AltName: Full=Urea amidohydrolase subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
GN   Name=ureB {ECO:0000255|HAMAP-Rule:MF_01954}; OrderedLocusNames=pNG7123;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OG   Plasmid pNG700.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=14981304; DOI=10.1271/bbb.68.397;
RA   Mizuki T., Kamekura M., DasSarma S., Fukushima T., Usami R., Yoshida Y.,
RA   Horikoshi K.;
RT   "Ureases of extreme halophiles of the genus Haloarcula with a unique
RT   structure of gene cluster.";
RL   Biosci. Biotechnol. Biochem. 68:397-406(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809; PLASMID=pNG700;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01954};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC       subunits. Three heterotrimers associate to form the active enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SIMILARITY: Belongs to the urease beta subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
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DR   EMBL; AB119092; BAC84957.1; -; Genomic_DNA.
DR   EMBL; AY596296; AAV44834.1; -; Genomic_DNA.
DR   RefSeq; WP_011222585.1; NZ_CP039137.1.
DR   AlphaFoldDB; Q75ZQ6; -.
DR   SMR; Q75ZQ6; -.
DR   EnsemblBacteria; AAV44834; AAV44834; pNG7123.
DR   GeneID; 40151395; -.
DR   KEGG; hma:pNG7123; -.
DR   PATRIC; fig|272569.17.peg.566; -.
DR   HOGENOM; CLU_129707_2_1_2; -.
DR   OMA; FYEVNDA; -.
DR   BRENDA; 3.5.1.5; 2549.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000001169; Plasmid pNG700.
DR   GO; GO:0035550; C:urease complex; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Plasmid; Reference proteome.
FT   CHAIN           1..138
FT                   /note="Urease subunit beta"
FT                   /id="PRO_0000234283"
FT   REGION          115..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   138 AA;  14476 MW;  65DBD39EFA633F46 CRC64;
     MSDGLVPGEV IPGEGTVTLN EGRERTEVTV GNTGDRPSQV GSHFHFFEAN AALEFDREAA
     MGMRLNIPAG TAVRFEPGDE QTVELVEIGG KRRAHGMNGL VNGSVDGETG DAVERMRAAG
     FGDTGEAAPD DGDTESDQ