ID   URE2_UREPA              Reviewed;         124 AA.
AC   P0C7K8; Q56558;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Urease subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
DE            EC=3.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01954};
DE   AltName: Full=Urea amidohydrolase subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
GN   Name=ureB {ECO:0000255|HAMAP-Rule:MF_01954}; OrderedLocusNames=UU433;
OS   Ureaplasma parvum serovar 3 (strain ATCC 700970).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=273119;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27813 / 7 / Serovar 1;
RX   PubMed=8550495; DOI=10.1128/jb.178.3.647-655.1996;
RA   Neyrolles O., Ferris S., Behbahani N., Montagnier L., Blanchard A.;
RT   "Organization of Ureaplasma urealyticum urease gene cluster and expression
RT   in a suppressor strain of Escherichia coli.";
RL   J. Bacteriol. 178:647-655(1996).
RN   [2]
RP   ERRATUM OF PUBMED:8550495.
RX   PubMed=8626347; DOI=10.1128/jb.178.9.2725-2725.1996;
RA   Neyrolles O., Ferris S., Behbahani N., Montagnier L., Blanchard A.;
RL   J. Bacteriol. 178:2725-2725(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27813 / 7 / Serovar 1, ATCC 27818 / Pi / Serovar 6, and
RC   ATCC 33697 / U26 / Serovar 14;
RX   PubMed=10555372; DOI=10.1099/00207713-49-4-1879;
RA   Kong F., James G., Ma Z., Gordon S., Wang B., Gilbert G.L.;
RT   "Phylogenetic analysis of Ureaplasma urealyticum -- support for the
RT   establishment of a new species, Ureaplasma parvum.";
RL   Int. J. Syst. Bacteriol. 49:1879-1889(1999).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700970;
RX   PubMed=11048724; DOI=10.1038/35037619;
RA   Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y.,
RA   Cassell G.H.;
RT   "The complete sequence of the mucosal pathogen Ureaplasma urealyticum.";
RL   Nature 407:757-762(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01954};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC       subunits. Three heterotrimers associate to form the active enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SIMILARITY: Belongs to the urease beta subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
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DR   EMBL; L40489; AAA89188.2; -; Genomic_DNA.
DR   EMBL; AF085730; AAD28135.1; -; Genomic_DNA.
DR   EMBL; AF085731; AAD28138.1; -; Genomic_DNA.
DR   EMBL; AF085733; AAD28144.1; -; Genomic_DNA.
DR   EMBL; AF222894; AAF30845.1; -; Genomic_DNA.
DR   PIR; H82890; H82890.
DR   RefSeq; WP_006688518.1; NC_002162.1.
DR   AlphaFoldDB; P0C7K8; -.
DR   SMR; P0C7K8; -.
DR   STRING; 273119.UU433; -.
DR   EnsemblBacteria; AAF30845; AAF30845; UU433.
DR   GeneID; 29672369; -.
DR   KEGG; uur:UU433; -.
DR   eggNOG; COG0832; Bacteria.
DR   HOGENOM; CLU_129707_1_1_14; -.
DR   OMA; FYEVNDA; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000000423; Chromosome.
DR   GO; GO:0035550; C:urease complex; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..124
FT                   /note="Urease subunit beta"
FT                   /id="PRO_0000067583"
SQ   SEQUENCE   124 AA;  13509 MW;  743DDE240805F1F5 CRC64;
     MSGSSSQFSP GKLVPGAINF ASGEIVMNEG REAKVISIKN TGDRPIQVGS HFHLFEVNSA
     LVFFDEKGNE DKERKVAYGR RFDIPSGTAI RFEPGDKKEV SIIDLAGTRE VWGVNGLVNG
     KLKK