ID   URE2_UREU1              Reviewed;         124 AA.
AC   B5ZBT0; P17273; Q9WVU8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Urease subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
DE            EC=3.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01954};
DE   AltName: Full=Urea amidohydrolase subunit beta {ECO:0000255|HAMAP-Rule:MF_01954};
GN   Name=ureB {ECO:0000255|HAMAP-Rule:MF_01954}; OrderedLocusNames=UUR10_0478;
OS   Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=565575;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10555372; DOI=10.1099/00207713-49-4-1879;
RA   Kong F., James G., Ma Z., Gordon S., Wang B., Gilbert G.L.;
RT   "Phylogenetic analysis of Ureaplasma urealyticum -- support for the
RT   establishment of a new species, Ureaplasma parvum.";
RL   Int. J. Syst. Bacteriol. 49:1879-1889(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33699 / Western;
RA   Shrivastava S., Methe B.A., Glass J., White K., Duffy L.B.;
RT   "Genome sequence of Ureaplasma urealyticum serovar 10 ATCC-33699.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01954};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC       subunits. Three heterotrimers associate to form the active enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01954}.
CC   -!- SIMILARITY: Belongs to the urease beta subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01954}.
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DR   EMBL; AF085726; AAD28123.1; -; Genomic_DNA.
DR   EMBL; CP001184; ACI59941.1; -; Genomic_DNA.
DR   RefSeq; WP_004025930.1; NC_011374.1.
DR   AlphaFoldDB; B5ZBT0; -.
DR   SMR; B5ZBT0; -.
DR   STRING; 565575.UUR10_0478; -.
DR   EnsemblBacteria; ACI59941; ACI59941; UUR10_0478.
DR   GeneID; 45016021; -.
DR   KEGG; uue:UUR10_0478; -.
DR   eggNOG; COG0832; Bacteria.
DR   HOGENOM; CLU_129707_1_1_14; -.
DR   OMA; FYEVNDA; -.
DR   OrthoDB; 1755809at2; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000002018; Chromosome.
DR   GO; GO:0035550; C:urease complex; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..124
FT                   /note="Urease subunit beta"
FT                   /id="PRO_1000188946"
SQ   SEQUENCE   124 AA;  13608 MW;  00C909AE921BF23C CRC64;
     MSGSSNQFTP GKLVPGAINF AEGEIVMNEG REAKVISIKN TGDRPIQVGS HFHLFETNSA
     LVFFDEKGNE DKERKVAYGR RFDIPSGTAI RFEPGDKKEV SVIDLVGTRE VWGVNGLVNG
     KLKK