ID   URE3_STRTR              Reviewed;         100 AA.
AC   Q83U21;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Urease subunit gamma {ECO:0000255|HAMAP-Rule:MF_00739};
DE            EC=3.5.1.5 {ECO:0000255|HAMAP-Rule:MF_00739};
DE   AltName: Full=Urea amidohydrolase subunit gamma {ECO:0000255|HAMAP-Rule:MF_00739};
GN   Name=ureA {ECO:0000255|HAMAP-Rule:MF_00739};
OS   Streptococcus thermophilus.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 19258 / DSM 20617 / LMG 6896 / NCDO 573 / NCIMB 8510;
RX   PubMed=14678176; DOI=10.1046/j.1365-2672.2003.02148.x;
RA   Mora D., Maguin E., Masiero M., Parini C., Ricci G., Manachini P.L.,
RA   Daffonchio D.;
RT   "Characterization of urease genes cluster of Streptococcus thermophilus.";
RL   J. Appl. Microbiol. 96:209-219(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Anba-Mondoloni J., Renault P., Ehrlich S.D.;
RT   "Characterization of Streptococcus thermophilus urease operon.";
RL   Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00739};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_00739}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC       subunits. Three heterotrimers associate to form the active enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_00739}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00739}.
CC   -!- SIMILARITY: Belongs to the urease gamma subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_00739}.
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DR   EMBL; AJ544512; CAD67481.1; -; Genomic_DNA.
DR   EMBL; AF362908; AAO37370.1; -; Genomic_DNA.
DR   RefSeq; WP_002886558.1; NZ_WMLD01000009.1.
DR   AlphaFoldDB; Q83U21; -.
DR   SMR; Q83U21; -.
DR   STRING; 322159.STER_0323; -.
DR   GeneID; 61564318; -.
DR   GeneID; 66898206; -.
DR   eggNOG; COG0831; Bacteria.
DR   OMA; MQLTPHE; -.
DR   UniPathway; UPA00258; UER00370.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_00739; Urease_gamma; 1.
DR   InterPro; IPR012010; Urease_gamma.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001223; Urease_gamma; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase.
FT   CHAIN           1..100
FT                   /note="Urease subunit gamma"
FT                   /id="PRO_0000098051"
SQ   SEQUENCE   100 AA;  11299 MW;  8F7A87B354FABF7B CRC64;
     MQLTMREQEK MMISLAAMIA QRRKDKGIKL NHPEAVALIT DYVLEGAREG KTVAQLMDEA
     RNLLTREDVM EGIAEMIPMI QVEATFTDST KLVTVHDPIQ