ID   URED1_BRUAB             Reviewed;         280 AA.
AC   Q57F88;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Urease accessory protein UreD 1 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD1 {ECO:0000255|HAMAP-Rule:MF_01384}; Synonyms=ureD-1;
GN   OrderedLocusNames=BruAb1_0293;
OS   Brucella abortus biovar 1 (strain 9-941).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=262698;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9-941;
RX   PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA   Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA   Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT   "Completion of the genome sequence of Brucella abortus and comparison to
RT   the highly similar genomes of Brucella melitensis and Brucella suis.";
RL   J. Bacteriol. 187:2715-2726(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AE017223; AAX73696.1; -; Genomic_DNA.
DR   RefSeq; WP_002963430.1; NC_006932.1.
DR   AlphaFoldDB; Q57F88; -.
DR   SMR; Q57F88; -.
DR   EnsemblBacteria; AAX73696; AAX73696; BruAb1_0293.
DR   GeneID; 3789049; -.
DR   KEGG; bmb:BruAb1_0293; -.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   OMA; MARFCAQ; -.
DR   Proteomes; UP000000540; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..280
FT                   /note="Urease accessory protein UreD 1"
FT                   /id="PRO_0000340417"
SQ   SEQUENCE   280 AA;  30256 MW;  3FE5CA77016C952C CRC64;
     MLIINDNNLS GLSLQRVNGT GELSVQFKDG RSRISRLYQE GAAKIRMPQA VTGPLEAILI
     NTSGGLTGGD RLKWDVALDD GASAVITTQA CERIYRSGGG EARIATRLKA AKGTRLAWLP
     QETILFNRSI LSRRLDVELE EGAQMLVVEA TVFGRLAMGE RVVAARFADR WRVRLGGRVI
     HAEEFRLGPD VGAELQAPAV AGGACAMATV LMVCEQAGRY LETARAIIGE EGGCSLWRVG
     KASKLVVRLY APDSYALRRR LCPLVALLNG KAGLPKVWTI