ID   URED1_PSEU2             Reviewed;         285 AA.
AC   Q4ZUD4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Urease accessory protein UreD 1 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD1 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Psyr_2195;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000075; AAY37238.1; -; Genomic_DNA.
DR   RefSeq; WP_011267495.1; NC_007005.1.
DR   RefSeq; YP_235276.1; NC_007005.1.
DR   AlphaFoldDB; Q4ZUD4; -.
DR   SMR; Q4ZUD4; -.
DR   STRING; 205918.Psyr_2195; -.
DR   EnsemblBacteria; AAY37238; AAY37238; Psyr_2195.
DR   KEGG; psb:Psyr_2195; -.
DR   PATRIC; fig|205918.7.peg.2246; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_0_6; -.
DR   OMA; PYPFHIT; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..285
FT                   /note="Urease accessory protein UreD 1"
FT                   /id="PRO_0000346588"
SQ   SEQUENCE   285 AA;  30575 MW;  A23476A2BBE2C7FC CRC64;
     MNAHQSSLPA QTKRTAHIAF SKAPSGASYV SRQEVGYPFH LGRTLTLPQD PPGMAAVYLQ
     SCSGGLFAGE QLHLHLHAGP GTQVHVSTGA ATVAHSMLEQ SARQTVTLVA EADALLEYLP
     MATILFPQTR LHSQVNVTLH PGARVLLCDA FCLHTPHGSE GLPDFYRADL QVYSPAGKLL
     AGDRLAITGA DLQRRLPGVS GQRQALATFM LVGQGLPIED LKRTLRETLR DVADSYQGVS
     ALPNDCGVSV RVMSADAVAL RNALHLAWAC VRQQLTGLAP RVRRK